Severe covid-19 pneumonia: pathogenesis and clinical management

AH Attaway, RG Scheraga, A Bhimraj, M Biehl… - bmj, 2021 - bmj.com
Severe covid-19 pneumonia has posed critical challenges for the research and medical
communities. Older age, male sex, and comorbidities increase the risk for severe disease …

Incidence of ARDS and outcomes in hospitalized patients with COVID-19: a global literature survey

SJ Tzotzos, B Fischer, H Fischer, M Zeitlinger - Critical Care, 2020 - Springer
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) appeared just over 7 months ago in Wuhan, China. Early …

Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study

C Karagiannidis, C Mostert, C Hentschker… - The Lancet …, 2020 - thelancet.com
Background Nationwide, unbiased, and unselected data of hospitalised patients with COVID-
19 are scarce. Our aim was to provide a detailed account of case characteristics, resource …

[HTML][HTML] COVID-19-associated acute respiratory distress syndrome: is a different approach to management warranted?

E Fan, JR Beitler, L Brochard, CS Calfee… - The Lancet …, 2020 - thelancet.com
The COVID-19 pandemic has seen a surge of patients with acute respiratory distress
syndrome (ARDS) in intensive care units across the globe. As experience of managing …

Case fatality rates for patients with COVID-19 requiring invasive mechanical ventilation. A meta-analysis

ZJ Lim, A Subramaniam, M Ponnapa Reddy… - American journal of …, 2021 - atsjournals.org
Rationale: Initial reports of case fatality rates (CFRs) among adults with coronavirus disease
(COVID-19) receiving invasive mechanical ventilation (IMV) are highly variable. Objectives …

Effect of timing of intubation on clinical outcomes of critically ill patients with COVID-19: a systematic review and meta-analysis of non-randomized cohort studies

E Papoutsi, VG Giannakoulis, E Xourgia, C Routsi… - Critical Care, 2021 - Springer
Background Although several international guidelines recommend early over late intubation
of patients with severe coronavirus disease 2019 (COVID-19), this issue is still controversial …

COVID-19 pneumonia: pathophysiology and management

L Gattinoni, S Gattarello, I Steinberg… - European …, 2021 - Eur Respiratory Soc
Coronavirus disease 2019 (COVID-19) pneumonia is an evolving disease. We will focus on
the development of its pathophysiologic characteristics over time, and how these time …

Mechanical ventilation parameters in critically ill COVID-19 patients: a scoping review

G Grasselli, E Cattaneo, G Florio, M Ippolito, A Zanella… - Critical Care, 2021 - Springer
Background The mortality of critically ill patients with COVID-19 is high, particularly among
those receiving mechanical ventilation (MV). Despite the high number of patients treated …

Timing of intubation and mortality among critically ill coronavirus disease 2019 patients: a single-center cohort study

AC Hernandez-Romieu, MW Adelman… - Critical care …, 2020 - journals.lww.com
Objectives: Increasing time to mechanical ventilation and high-flow nasal cannula use may
be associated with mortality in coronavirus disease 2019. We examined the impact of time to …

Effects of COVID-19 on the musculoskeletal system: clinician's guide

LK Hasan, B Deadwiler, A Haratian… - … research and reviews, 2021 - Taylor & Francis
The global pandemic caused by SARS-CoV-2, or COVID-19, continues to impact all facets of
daily life. Clinical manifestations of COVID-19 commonly include musculoskeletal symptoms …