A review on advances in synthetic methodology and biological profile of spirothiazolidin‐4‐ones

J Yadav, RP Chaudhary - Journal of Heterocyclic Chemistry, 2022 - Wiley Online Library
Heterocycles are important structural components in pharmacophores that are currently
being used to treat several diseases. Among the various heterocyclic scaffolds, nitrogen and …

[PDF][PDF] Synthesis and antioxidant properties of novel 2-(2, 4-dioxothiazolidin-5-ylidene)-acetamides containing 1, 3, 4-thia/oxadiazole moieties

M Lelyukh, M Yu, V Flud, I Chaban… - … Res. Appl. Chem, 2022 - biointerfaceresearch.com
A series of novel 1, 3, 4-thia (oxa) diazole substituted 2-(2, 4-dioxothiazolidine-5-ylidene)-
acetamides 3a-c, 4 and 5a-k have been synthesized following the acylation reaction of 2 …

In‐vitro antiviral screening of some thiopyranothiazoles

A Kryshchyshyn-Dylevych, D Kaminskyy… - Chemico-Biological …, 2023 - Elsevier
Thiopyranothiazoles represent a promising class of drug-like molecules with broad
pharmacological profiles. Some novel derivatives of isothiochromeno [4a, 4-d] thiazole and …

Synthesis of 5-aryl/heterylidene substituted 2-imino-4-thiazolidinones possessing 1, 3, 4-thiadiazole moiety and their antitrypanosomal activity

M Lelyukh, H Halevych, M Zhukrovska… - Current Chemistry …, 2023 - m.growingscience.com
A novel 1, 3, 4-thiadiazole containing 2-iminothiazolidine-4-ones 4a-b were synthesized
through the reaction of 2-chloro-N-(5-ethyl/allylsulfanyl-[1, 3, 4] thiadiazol-2-yl)-acetamides …

Synthesis of new N‐(3‐oxo‐1‐thia‐4‐azaspiro[4.5]decan‐4‐yl)pyridine‐3‐carboxamide derivatives and evaluation of their anti‐influenza virus and antitubercular …

G Cihan‑Üstündağ, Ç Acar, L Naesens… - Archiv der …, 2022 - Wiley Online Library
We here report the synthesis, structural characterization, and evaluation of the antiviral and
antitubercular activities of a novel series of hybrid spirothiazolidinone derivatives (2a–f and …

Synthesis, Characterization, Molecular Docking, and Computational Study of novel Spirothiazolidinone Compounds

MG Mukhlif, OJ Mahdi, MJ Bichan - Journal of Molecular Structure, 2025 - Elsevier
An essential component in the formation of organic molecules is cyclohexanone. This makes
cyclohexanone a good choice for use in organic synthesis because the carbonyl group is …

One-pot synthesis, characterization and antiviral properties of new benzenesulfonamide-based spirothiazolidinones

ÇB Apaydın, L Naesens, G Cihan-Üstündağ - Molecular Diversity, 2024 - Springer
A novel series of benzenesulfonamide substituted spirothiazolidinone derivatives (3a–j)
were synthesized, characterized and evaluated for their antiviral activity. The spirocyclic …

Expeditious mechanochemical conversion of dihydronaphthalenyl-N-phenylhydrazine-1-carbothioamides into hydrazono-thiazolidin-4-one and hydrazono …

S Goswami, RP Chaudhary - … , Sulfur, and Silicon and the Related …, 2023 - Taylor & Francis
This study reports a facile mechanochemical conversion of N-phenylthiosemicarbazone
derivatives of 1-tetralone analogs into thiazolidin-4-ones, thiazolidin-5-ylidene-acetates, and …