GABA-A receptors are the major inhibitory neurotransmitter receptors in the brain and are
the site of action of many clinically important drugs. These receptors are composed of five …

This review focuses on the unique clinical and molecular pharmacology of etomidate.
Among general anesthesia induction drugs, etomidate is the only imidazole, and it has the …

GABAA receptors are ligand-operated chloride channels assembled from five subunits in a
heteropentameric manner. Using immunocytochemistry, we investigated the distribution of …

GABAA receptors are ligand-gated chloride channels and ionotropic receptors of GABA, the
main inhibitory neurotransmitter in vertebrates. In this review, we discuss the major and …

Our original review,“Heterogeneity and Diversity of Striatal GABAergic Interneurons,” to
which this is an invited update, was published in December, 2010 in Frontiers is …

Neostriatal cholinergic interneurons are believed to be important for reinforcement-mediated
learning and response selection by signaling the occurrence and motivational value of …

In some nerve cells, activation of GABAA receptors by GABA results in phasic and tonic
conductances. Transient activation of synaptic receptors generates phasic inhibition …

The cellular and subcellular distribution of four GABAA receptor subtypes, identified by the
presence of the α1, α2, α3, or α5 subunit, was investigated immunocytochemically in …

Immunocytochemical visualization of the neuron‐specific K+/Cl–cotransporter, KCC2, at the
cellular and subcellular level revealed an area‐and layer‐specific diffuse labelling, and a …

Functionally, γ-aminobutyric acid receptor (GABAR)–mediated inhibition can be classified as
phasic (synaptic) and tonic (extrasynaptic). The GABARs underlying tonic inhibition …