After nearly four decades of research, a safe and effective HIV-1 vaccine remains elusive.
There are many reasons why the development of a potent and durable HIV-1 vaccine is …

Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by
antinuclear antibodies (ANAs) that form immune complexes that mediate pathogenesis by …

MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

Despite antiretroviral therapy (ART), human immunodeficiency virus (HIV)-1 persists in a
stable latent reservoir,, primarily in resting memory CD4+ T cells,. This reservoir presents a …

Understanding gut microbiota alterations associated with HIV infection and factors that drive
these alterations may help explain gut-linked diseases prevalent with HIV. 16S rRNA …

This review examines the enormous progress that has been made in the past decade in
understanding the origin of HIV, HIV genetic variability, and the impact of global HIV diversity …

Infectious and inflammatory diseases have repeatedly shown strong genetic associations
within the major histocompatibility complex (MHC); however, the basis for these associations …

Latent reservoirs of HIV-1-infected cells are refractory to antiretroviral therapies (ART) and
remain the major barrier to curing HIV-1. Because latently infected cells are long-lived …

The development of an effective vaccine has been hindered by the enormous diversity of
human immunodeficiency virus‐1 (HIV‐1) and its ability to escape a myriad of host immune …

Background It is unknown if extremely early initiation of antiretroviral therapy (ART) may lead
to long-term ART-free HIV remission or cure. As a result, we studied 2 individuals recruited …