Mucosal surfaces are key interfaces between the host and its environment, but also
constitute ports of entry for numerous pathogens. The gut and lung mucosae act as points of …

Dendritic cells (DCs) play important roles in orchestrating host immunity against invading
pathogens, representing one of the first responders to infection by mucosal invaders. From …

HIV viral reservoirs are established very early during infection. Resident memory T cells
(TRM) are present in tissues such as the lower female genital tract, but the contribution of …

Langerhans cells (LC) are thought to be the only mononuclear phagocyte population in the
epidermis where they detect pathogens. Here, we show that CD11c+ dendritic cells (DCs) …

Dendritic cells (DCs) are professional antigen-presenting cells that link innate and adaptive
immunity and are critical for the induction of protective immune responses against …

Microbial infections are a threat to women's reproductive health. Although reproductive
cycles and pregnancy are controlled by sex hormones, the impact of hormones on host …

Tissue mononuclear phagocytes (MNP) are specialised in pathogen detection and antigen
presentation. As such they deliver HIV to its primary target cells; CD4 T cells. Most MNP HIV …

Acquired immunodeficiency syndrome (AIDS), caused by the human immunodeficiency
virus (HIV), has become a heavy burden of disease and an important public health problem …

Dendritic cells (DCs) play critical roles in HIV pathogenesis and require further investigation
in the female genital tract, a main portal of entry for HIV infection. Here we characterized …

In the context of HIV sexual transmission at the genital mucosa, initial interactions between
the virus and the mucosal immunity determine the outcome of the exposure. Hence, these …