The role of JAK/STAT signaling pathway and its inhibitors in diseases
P Xin, X Xu, C Deng, S Liu, Y Wang, X Zhou… - International …, 2020 - Elsevier
The JAK/STAT signaling pathway is an universally expressed intracellular signal
transduction pathway and involved in many crucial biological processes, including cell …
transduction pathway and involved in many crucial biological processes, including cell …
Antioxidant Activity of Leaf Extracts from Stevia rebaudiana Bertoni Exerts Attenuating Effect on Diseased Experimental Rats: A Systematic Review and Meta-Analysis
Stevia (Stevia rebaudiana Bertoni) is an aromatic plant known for its high sweetening power
ascribed to its glycosides. Stevia also contains several bioactive compounds showing …
ascribed to its glycosides. Stevia also contains several bioactive compounds showing …
The inflammatory bowel disease transcriptome and metatranscriptome meta-analysis (IBD TaMMA) framework
Inflammatory bowel disease (IBD) is a class of chronic disorders whose etiogenesis is still
unknown. Despite the high number of IBD-related omics studies, the RNA-sequencing data …
unknown. Despite the high number of IBD-related omics studies, the RNA-sequencing data …
[HTML][HTML] The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models
Understanding how genetic variants impact molecular phenotypes is a key goal of functional
genomics, currently hindered by reliance on a single haploid reference genome. Here, we …
genomics, currently hindered by reliance on a single haploid reference genome. Here, we …
Meta-analysis of gene expression disease signatures in colonic biopsy tissue from patients with ulcerative colitis
Publicly available ulcerative colitis (UC) gene expression datasets from observational
studies and clinical trials include inherently heterogeneous disease characteristics and …
studies and clinical trials include inherently heterogeneous disease characteristics and …
Mapping Transcriptome Data to Protein–Protein Interaction Networks of Inflammatory Bowel Diseases Reveals Disease-Specific Subnetworks
SF Maden, SE Acuner - Frontiers in genetics, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) is the common name for chronic disorders associated with
the inflammation of the gastrointestinal tract. IBD is triggered by environmental factors in …
the inflammation of the gastrointestinal tract. IBD is triggered by environmental factors in …
[HTML][HTML] Methods for multiple outcome meta-analysis of gene-expression data
Meta-analysis is a valuable tool for the synthesis of evidence across a wide range study
types including high-throughput experiments such as genome-wide association studies …
types including high-throughput experiments such as genome-wide association studies …
To seal or not to seal following an antimicrobial infusion at dry-off? A systematic review and multivariate meta-analysis of the incidence and prevalence of …
Teat sealants (TSs) consist of sterile formulations with no antibacterial activity. Alone or in
combination with antimicrobial (AM) or non-AM treatments, TSs have been commonly used …
combination with antimicrobial (AM) or non-AM treatments, TSs have been commonly used …
Gene expression profiling of early Parkinson's disease patient reveals redox homeostasis
L Zhang, Y He, K Lei, Z Fang, Q Li, J Su, Z Nie, Y Xu… - Neuroscience …, 2021 - Elsevier
Parkinson's disease (PD) is slowly progressive. Due to the lack of specific and sensitive
biomarkers, the majority of PD patients are in the advanced stages when diagnosed. This …
biomarkers, the majority of PD patients are in the advanced stages when diagnosed. This …
[PDF][PDF] Using genomic approaches to characterise the immune response to biologicals
S Lin - 2023 - ore.exeter.ac.uk
Biologic therapies are effective treatments for inflammatory bowel disease (IBD). Successful
treatment leads to reduced hospitalisation and surgeries, and an improvement in quality of …
treatment leads to reduced hospitalisation and surgeries, and an improvement in quality of …