Acanthopanax senticosus improves cognitive impairment in Alzheimer's disease by promoting the phosphorylation of the MAPK signaling pathway

Z Zhang, Y Wu, D Shi, C Jiang, H Cao, F Jiang… - Frontiers in …, 2024 - frontiersin.org
Background Acanthopanax senticosus (AS) can improve sleep, enhance memory, and
reduce fatigue and is considered as an effective drug for Alzheimer's disease (AD). The …

Assessing Cannabidiol as a Therapeutic Agent for Preventing and Alleviating Alzheimer's Disease Neurodegeneration

L Chen, Y Sun, J Li, S Liu, H Ding, G Wang, X Li - Cells, 2023 - mdpi.com
Alzheimer's disease (AD) is a leading neurodegenerative condition causing cognitive and
memory decline. With small-molecule drugs targeting Aβ proving ineffective, alternative …

The standardized extract of Centella asiatica and its fractions exert antioxidative and anti-neuroinflammatory effects on microglial cells and regulate the Nrf2/HO-1 …

A Hambali, NA Jusril, NF Md Hashim… - Journal of …, 2024 - content.iospress.com
Background: Neuroinflammation and oxidative stress can aggravate the progression of
Alzheimer's disease (AD). Centella asiatica has been traditionally consumed for memory …

Benzyloxychalcone Hybrids as Prospective Acetylcholinesterase Inhibitors against Alzheimer's Disease: Rational Design, Synthesis, In Silico ADMET Prediction …

HM Al-Maqtari, AH Hasan, M Suleiman… - ACS …, 2024 - ACS Publications
Acetylcholinesterase inhibitors (AChEIs) are crucial therapeutic targets for both the early and
severe stages of Alzheimer's disease (AD). Chalcones and their chromone-based …

Asiaticoside alleviates lipopolysaccharide-induced acute lung injury by blocking Sema4D/CD72 and inhibiting mitochondrial dysfunction in RAW264. 7 cell and mice

J Zhang, H Zhao, F Wang, J Zhou, M Li, H Li… - Naunyn-Schmiedeberg's …, 2024 - Springer
Acute lung injury (ALI) is a common disease with complex pathogenesis. However, the
treatment is mainly symptomatic with limited clinical options. Asiaticoside (AS), a Chinese …

Neuroprotective prospectives of triterpenoids

AA Bankar, VP Nagulwar, NR Kotagale… - Exploration of …, 2024 - explorationpub.com
Neurological disorders including neurodegenerative disorders continue to pose significant
therapeutic challenges. Triterpenoids, a diverse group of natural compounds found …

[PDF][PDF] Evoluzione nella terapia della malattia di Alzheimer: dagli inibitori dell'acetilcolinesterasi agli anticorpi monoclonali

C ZANCHETTA - 2023 - unitesi.uniupo.it
Il morbo di Alzheimer (AD) rappresenta una delle sfide piu complesse per la medicina
moderna, essendo la forma piu comune di demenza e colpendo milioni di persone in tutto il …

[HTML][HTML] Centella asiatica Promotes Antioxidant Gene Expression and Mitochondrial Oxidative Respiration in Experimental Autoimmune Encephalomyelitis

P Kundu, K Yasuhara, MS Brandes, JA Zweig, CJ Neff… - Pharmaceuticals, 2024 - mdpi.com
Background/Objectives: Centella asiatica (L.) Urban (family Apiaceae)(C. asiatica) is a
traditional botanical medicine used in aging and dementia. Water extracts of C. asiatica …