In the search for interventions against aging and age-related diseases, biological screening
platforms are indispensable tools to identify anti-aging compounds among large substance …

Worldwide morbidity and mortality from acute myocardial infarction (AMI) and related heart
failure remain high. While effective early reperfusion of the criminal coronary artery after a …

Huntington's disease (HD) is a neurodegenerative disorder that leads to progressive
neuronal loss, provoking impaired motor control, cognitive decline, and dementia. So far, HD …

Fingolimod hydrochloride (FTY720) is a first‐in‐class of sphingosine‐1‐phosphate (S1P)
receptor modulator approved to treat multiple sclerosis by its phosphorylated form (FTY720 …

Discovering new drugs for treatment of invasive fungal infections is an enduring challenge.
There are only three major classes of antifungal agents, and no new class has been …

Edge effect denotes better growth of microbial organisms situated at the edge of the solid
agar media. Although the precise reason underlying edge effect is unresolved, it is generally …

Abstract FTY720, a sphingosine‐1‐phosphate (S1P) analog, is used as an immune
modulator to treat multiple sclerosis. Accumulating evidence has suggested the mode of …