NAD+ was discovered during yeast fermentation, and since its discovery, its important roles
in redox metabolism, aging, and longevity, the immune system and DNA repair have been …

Tissue regeneration is an active multiplex process involving the dynamic inflammatory
microenvironment. Under a normal physiological framework, inflammation is necessary for …

Diabetic infectious microenvironment (DIME) frequently leads to a critical failure of
osseointegration by virtue of its main peculiarities including typical hyperglycemia and …

Cancer cells, particularly in solid tumors, are surrounded by non-neoplastic elements,
including endothelial and stromal cells, as well as cells of immune origin, which can support …

Macrophages play an important role in regulating the tumor microenvironment (TME). Here
we show that classical (M1) macrophage polarization reduced expression of LSD1, nuclear …

Anti-CD19 chimeric antigen receptor (CAR)-T cell therapy has achieved 40%–50% long-
term complete response in relapsed or refractory diffuse large B-cell lymphoma (DLBCL) …

Most somatic cells secrete vesicles called exosomes, which contain a variety of
biomolecules. Recent research indicates that macrophage-derived exosomes are strongly …

The (M2M+ TGF-β)@ HAMA hydrogel dressing improves the outcomes of dysregulated
chronic wound healing by protecting the open wound from repeated bacterial infections …

Malignant tumor cells exhibit mitochondrial alterations and are also influenced by
biobehavioral processes, but the intersection of biobehavioral factors and mitochondria in …

Macrophages are important members of the innate immune system that can be reversibly
polarized by different microenvironment signals. Exosomes secreted from cells are lipid …