The prevalence and incidence of NAFLD worldwide: a systematic review and meta-analysis
Background Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease
worldwide and the leading cause of liver-related morbidity and mortality. We aimed to …
worldwide and the leading cause of liver-related morbidity and mortality. We aimed to …
A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement
The exclusion of other chronic liver diseases including “excess” alcohol intake has until now
been necessary to establish a diagnosis of metabolic dysfunction-associated fatty liver …
been necessary to establish a diagnosis of metabolic dysfunction-associated fatty liver …
AASLD Practice Guidance on the clinical assessment and management of nonalcoholic fatty liver disease
ME Rinella, BA Neuschwander-Tetri, MS Siddiqui… - Hepatology, 2023 - journals.lww.com
Abbreviations: AASLD, American Association for the Study of Liver Diseases; AI, artificial
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …
intelligence; ALT, alanine aminotransferase; AST, aspartate aminotransferase; AUROC …
EASL Clinical Practice Guidelines on non-invasive tests for evaluation of liver disease severity and prognosis–2021 update
Non-invasive tests are increasingly being used to improve the diagnosis and
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …
prognostication of chronic liver diseases across aetiologies. Herein, we provide the latest …
The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease
Metabolic associated fatty liver disease (MAFLD) is the principal worldwide cause of liver
disease and affects nearly a quarter of the global population. The objective of this work was …
disease and affects nearly a quarter of the global population. The objective of this work was …
Breakthroughs in therapies for NASH and remaining challenges
V Ratziu, S Francque, A Sanyal - Journal of hepatology, 2022 - Elsevier
Initially a condition that received limited recognition and whose clinical impact was
controversial, non-alcoholic steatohepatitis (NASH) has become a leading cause of chronic …
controversial, non-alcoholic steatohepatitis (NASH) has become a leading cause of chronic …
ACC inhibitor alone or co-administered with a DGAT2 inhibitor in patients with non-alcoholic fatty liver disease: two parallel, placebo-controlled, randomized phase 2a …
RA Calle, NB Amin, S Carvajal-Gonzalez, TT Ross… - Nature Medicine, 2021 - nature.com
Alterations in lipid metabolism might contribute to the pathogenesis of non-alcoholic fatty
liver disease (NAFLD). However, no pharmacological agents are currently approved in the …
liver disease (NAFLD). However, no pharmacological agents are currently approved in the …
Quantification of liver fat content with CT and MRI: state of the art
Hepatic steatosis is defined as pathologically elevated liver fat content and has many
underlying causes. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic …
underlying causes. Nonalcoholic fatty liver disease (NAFLD) is the most common chronic …
Noninvasive assessment of liver disease in patients with nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is estimated to afflict approximately 1 billion
individuals worldwide. In a subset of NAFLD patients, who have the progressive form of …
individuals worldwide. In a subset of NAFLD patients, who have the progressive form of …
Prospective evaluation of the prevalence of non-alcoholic fatty liver disease and steatohepatitis in a large middle-aged US cohort
SA Harrison, S Gawrieh, K Roberts, CJ Lisanti… - Journal of …, 2021 - Elsevier
Background & Aims Large prospective studies to establish the prevalence of non-alcoholic
fatty liver disease (NAFLD) and steatohepatitis (NASH), are lacking. We prospectively …
fatty liver disease (NAFLD) and steatohepatitis (NASH), are lacking. We prospectively …