Comprehensive insight into exploring the potential of microbial enzymes in cancer therapy: Progress, challenges, and opportunities: A review
FS Hassan, EM El-Fakharany, YA El-Maradny… - International Journal of …, 2024 - Elsevier
Microbial enzymes are crucial catalysts in various industries due to their versatility and
efficiency. The microbial enzymes market has recently expanded due to increased demand …
efficiency. The microbial enzymes market has recently expanded due to increased demand …
Engineering and expression strategies for optimization of L-Asparaginase development and production
AN Shishparenok, YA Gladilina… - International Journal of …, 2023 - mdpi.com
Genetic engineering for heterologous expression has advanced in recent years. Model
systems such as Escherichia coli, Bacillus subtilis and Pichia pastoris are often used as host …
systems such as Escherichia coli, Bacillus subtilis and Pichia pastoris are often used as host …
[HTML][HTML] The combination of calreticulin-targeting L-ASNase and anti-PD-L1 antibody modulates the tumor immune microenvironment to synergistically enhance the …
Y Zhang, V Akhil, HS Seo, HR Park, SH Kim, SH You… - Theranostics, 2024 - ncbi.nlm.nih.gov
Radiotherapy (RT) triggers immunogenic cell death (ICD). L-ASNase, which catalyzes the
conversion of asparagine (Asn), thereby depleting it, is used in the treatment of blood …
conversion of asparagine (Asn), thereby depleting it, is used in the treatment of blood …
Enhanced biochemical properties of soybean root nodule asparaginase through plant molecular farming compared to bacterial enzyme for cancer treatment
F Alharthi, HA Althagafi, I Jafri, AAA Oyouni… - Rhizosphere, 2024 - Elsevier
Asparaginase is a therapeutic enzyme used as an anticancer agent and is typically
produced through microbial fermentation using organisms such as Escherichia coli and …
produced through microbial fermentation using organisms such as Escherichia coli and …