[HTML][HTML] Circular RNAs: Characterization, cellular roles, and applications
CX Liu, LL Chen - Cell, 2022 - cell.com
Most circular RNAs are produced from the back-splicing of exons of precursor mRNAs.
Recent technological advances have in part overcome problems with their circular …
Recent technological advances have in part overcome problems with their circular …
Best practice standards for circular RNA research
AF Nielsen, A Bindereif, I Bozzoni, M Hanan… - Nature …, 2022 - nature.com
Circular RNAs (circRNAs) are formed in all domains of life and via different mechanisms.
There has been an explosion in the number of circRNA papers in recent years; however, as …
There has been an explosion in the number of circRNA papers in recent years; however, as …
Techniques for investigating lncRNA transcript functions in neurodevelopment
T Srinivas, E Siqueira, S Guil - Molecular Psychiatry, 2024 - nature.com
Long noncoding RNAs (lncRNAs) are sequences of 200 nucleotides or more that are
transcribed from a large portion of the mammalian genome. While hypothesized to have a …
transcribed from a large portion of the mammalian genome. While hypothesized to have a …
Circular RNA in disease: Basic properties and biomedical relevance
Circular RNAs (circRNAs) represent a class of covalently closed RNA molecules with great
diversity in molecular features, functions, and regulatory mechanisms. Emerging advances …
diversity in molecular features, functions, and regulatory mechanisms. Emerging advances …
NOVA2 regulates neural circRNA biogenesis
D Knupp, DA Cooper, Y Saito, RB Darnell… - Nucleic Acids …, 2021 - academic.oup.com
Circular RNAs (circRNAs) are highly expressed in the brain and their expression increases
during neuronal differentiation. The factors regulating circRNAs in the developing mouse …
during neuronal differentiation. The factors regulating circRNAs in the developing mouse …
circMbl functions in cis and in trans to regulate gene expression and physiology in a tissue-specific fashion
Muscleblind (mbl) is an essential muscle and neuronal splicing regulator. Mbl hosts multiple
circular RNAs (circRNAs), including circMbl, which is conserved from flies to humans. Here …
circular RNAs (circRNAs), including circMbl, which is conserved from flies to humans. Here …
Best practices to ensure robust investigation of circular RNAs: pitfalls and tips
Pre‐mRNAs from thousands of eukaryotic genes can be non‐canonically spliced to
generate circular RNAs (circRNAs) that have covalently linked ends. Most mature circular …
generate circular RNAs (circRNAs) that have covalently linked ends. Most mature circular …
Locus-conserved circular RNA cZNF292 controls endothelial cell flow responses
Background: Circular RNAs (circRNAs) are generated by back splicing of mostly mRNAs
and are gaining increasing attention as a novel class of regulatory RNAs that control various …
and are gaining increasing attention as a novel class of regulatory RNAs that control various …
[HTML][HTML] Emerging roles of circular RNAs in liver cancer
C Louis, D Leclerc, C Coulouarn - JHEP Reports, 2022 - Elsevier
Hepatocellular carcinoma and cholangiocarcinoma are the most common primary liver
tumours, whose incidence and associated mortality have increased over recent decades …
tumours, whose incidence and associated mortality have increased over recent decades …
Circular RNAs in cardiovascular diseases
In eukaryotes, precursor mRNAs (pre-mRNAs) produce a unique class of biologically active
molecules namely circular RNAs (circRNAs) with a covalently closed-loop structure via back …
molecules namely circular RNAs (circRNAs) with a covalently closed-loop structure via back …