S Mitra, J Anjum, M Muni, R Das, A Rauf, F Islam… - Biomedicine & …, 2022 - Elsevier
Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants, molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …
R Dang, M Wang, X Li, H Wang, L Liu, Q Wu… - Journal of …, 2022 - Springer
Background The inflammation and oxidative stress (OS) have been considered crucial components of the pathogenesis of depression. Edaravone (EDA), a free radical scavenger …
MMJ Van den Berg, J Krauskopf, JG Ramaekers… - Progress in …, 2020 - Elsevier
Circulating microRNAs (cimiRNAs) are a class of non-encoding RNAs found in bodily fluids such as blood, cerebrospinal fluid (CSF) and tears. CimiRNAs have been implicated as …
SIRT1 is a NAD+-dependent protein deacetylase that governs many physiological pathways, including circadian rhythm in peripheral tissues. Here, we show that SIRT1 in the …
The sirtuins are a family of highly conserved NAD+-dependent deacetylases that act as cellular sensors to detect energy availability and modulate metabolic processes. Two …
AZ Herskovits, L Guarente - Neuron, 2014 - cell.com
Sirtuins are nicotinamide adenine dinucleotide (NAD+)-dependent deacylases that have traditionally been linked with calorie restriction and aging in mammals. These proteins also …
A Kumar, J Pramanik, N Goyal, D Chauhan… - Pharmaceuticals, 2023 - mdpi.com
The gut microbiota is critical for maintaining human health and the immunological system. Several neuroscientific studies have shown the significance of microbiota in developing …
CA McClung - Biological psychiatry, 2013 - Elsevier
Mood disorders are serious diseases that affect a large portion of the population. There have been many hypotheses put forth over the years to explain the development of major …
N Begum, A Mandhare, KP Tryphena… - Frontiers in Aging …, 2022 - frontiersin.org
Gut-brain axis is a dynamic, complex, and bidirectional communication network between the gut and brain. Changes in the microbiota-gut-brain axis are responsible for developing …