Intimate partner violence-related brain injury: Unmasking and addressing the gaps

C Esopenko, D Jain, SP Adhikari… - Journal of …, 2024 - liebertpub.com
Intimate partner violence (IPV) is a significant, global public health concern. Women,
individuals with historically underrepresented identities, and disabilities are at high risk for …

Extracellular vesicle proteins and microRNAs as biomarkers for traumatic brain injury

VA Guedes, C Devoto, J Leete, D Sass, JD Acott… - Frontiers in …, 2020 - frontiersin.org
Traumatic brain injury (TBI) is a heterogeneous condition, associated with diverse etiologies,
clinical presentations and degrees of severity, and may result in chronic neurobehavioral …

Role of inflammation in traumatic brain injury–associated risk for neuropsychiatric disorders: State of the evidence and where do we go from here

VB Risbrough, MN Vaughn, SF Friend - Biological psychiatry, 2022 - Elsevier
In the past decade, there has been an increasing awareness that traumatic brain injury (TBI)
and concussion substantially increase the risk for developing psychiatric disorders. Even …

Ultrasensitive assays for detection of plasma tau and phosphorylated tau 181 in Alzheimer's disease: a systematic review and meta-analysis

X Ding, S Zhang, L Jiang, L Wang, T Li… - Translational …, 2021 - Springer
A lack of convenient and reliable biomarkers for diagnosis and prognosis is a common
challenge for neurodegenerative diseases such as Alzheimer's disease (AD). Recent …

One-year prospective study of plasma biomarkers from CNS in patients with mild traumatic brain injury

GJB Clarke, T Skandsen, H Zetterberg… - Frontiers in …, 2021 - frontiersin.org
Objective: To investigate the longitudinal evolution of three blood biomarkers: neurofilament
light (NFL), glial fibrillary acidic protein (GFAP) and tau, in out-patients and hospitalized …

Serum tau, neurofilament light chain, glial fibrillary acidic protein, and ubiquitin carboxyl-terminal hydrolase L1 are associated with the chronic deterioration of …

RT Lange, S Lippa, TA Brickell, J Gill… - Journal of …, 2023 - liebertpub.com
The purpose of this study was to examine the association of serum tau, neurofilament light
chain (NFL), glial fibrillary acidic protein (GFAP), and ubiquitin carboxy-terminal hydrolase …

Traumatic brain injury and the pathways to cerebral tau accumulation

WP Flavin, H Hosseini, JW Ruberti… - Frontiers in …, 2023 - frontiersin.org
Tau is a protein that has received national mainstream recognition for its potential negative
impact to the brain. This review succinctly provides information on the structure of tau and its …

[HTML][HTML] Neurochemical markers of traumatic brain injury: relevance to acute diagnostics, disease monitoring, and neuropsychiatric outcome prediction

P Shahim, H Zetterberg - Biological psychiatry, 2022 - Elsevier
Considerable advancements have been made in the quantification of biofluid-based
biomarkers for traumatic brain injury (TBI), which provide a clinically accessible window to …

The evolving role of extracellular vesicles (exosomes) as biomarkers in traumatic brain injury: Clinical perspectives and therapeutic implications

NA Khan, M Asim, A El-Menyar, KH Biswas… - Frontiers in Aging …, 2022 - frontiersin.org
Developing effective disease-modifying therapies for neurodegenerative diseases (NDs)
requires reliable diagnostic, disease activity, and progression indicators. While desirable …

Neuronally-derived tau is increased in experienced breachers and is associated with neurobehavioral symptoms

KA Edwards, K Greer, J Leete, C Lai, C Devoto… - Scientific reports, 2021 - nature.com
Military and law enforcement breachers are exposed to many low-level blasts during their
training and occupational experiences in which they detonate explosives to force entry into …