Atrial fibrillation (AF) is an increasingly prevalent arrhythmia; its pathophysiology and
progression are well studied. Stroke and bleeding risk models have been created and …

Atrial fibrillation (AF) is a worldwide epidemic associated with significant morbidity and
mortality, often due to disabling or fatal thromboembolic stroke. Oral anticoagulation is highly …

Background Published studies of epicardial ligation of left atrial appendage (LAA) have
reported discordant results. Objective The purpose of this study was to delineate the safety …

Background: The impact of left atrial appendage (LAA) exclusion, comparing an epicardial
LAA or an endocardial LAA device, on systemic homeostasis remains unknown. Objectives …

For many years, the left atrial appendage (LAA) was considered a dormant embryological
remnant; however, it is a structurally complex and functional organ that contributes to cardiac …

Background: Recent data suggest that epicardial left atrial appendage closure (LAAC) is
associated with several short-term neurohormonal effects. However, the long-term effects …

Left atrial appendage (LAA) closure has evolved as an effective strategy for stroke
prevention in patients with atrial fibrillation who are considered suitable for oral …

Atrial fibrillation (AF) is the most common atrial arrhythmia, but it is not a benign disease. AF
is an important risk factor for thromboembolic events, causing significant morbidity and …

Background: Percutaneous left atrial appendage exclusion (LAAE) has evolved as an
alternative strategy for stroke prevention in atrial fibrillation (AF). Recent observational data …

Background Left atrial (LA) strain (ε) and ε rate (SR) analysis by 2-dimensional speckle
tracking echocardiography is a novel method for functional assessment of the LA. Objective …