Advanced imaging tools for childhood tuberculosis: potential applications and research needs

SK Jain, S Andronikou, P Goussard… - The Lancet Infectious …, 2020 - thelancet.com
Tuberculosis is the leading cause of death globally that is due to a single pathogen, and up
to a fifth of patients with tuberculosis in high-incidence countries are children younger than …

Visualizing the dynamics of tuberculosis pathology using molecular imaging

AA Ordonez, EW Tucker, CJ Anderson… - The Journal of …, 2021 - Am Soc Clin Investig
Nearly 140 years after Robert Koch discovered Mycobacterium tuberculosis, tuberculosis
(TB) remains a global threat and a deadly human pathogen. M. tuberculosis is notable for …

Imaging bacteria with radiolabelled probes: is it feasible?

A Signore, V Artiko, M Conserva, G Ferro-Flores… - 2020 - mdpi.com
Bacterial infections are the main cause of patient morbidity and mortality worldwide.
Diagnosis can be difficult and delayed as well as the identification of the etiological …

Novel Treatments against Mycobacterium tuberculosis Based on Drug Repurposing

Á Mourenza, JA Gil, LM Mateos, M Letek - Antibiotics, 2020 - mdpi.com
Tuberculosis is the leading cause of death, worldwide, due to a bacterial pathogen. This
respiratory disease is caused by the intracellular pathogen Mycobacterium tuberculosis and …

Radionuclide imaging of apoptosis for clinical application

X Qin, H Jiang, Y Liu, H Zhang, M Tian - European journal of nuclear …, 2022 - Springer
Apoptosis was a natural, non-inflammatory, energy-dependent form of programmed cell
death (PCD) that can be discovered in a variety of physiological and pathological processes …

Development of [18F]ICMT-11 for Imaging Caspase-3/7 Activity during Therapy-Induced Apoptosis

SF García-Argüello, B Lopez-Lorenzo, B Cornelissen… - Cancers, 2020 - mdpi.com
Insufficient apoptosis is a recognised hallmark of cancer. A strategy to quantitatively
measure apoptosis in vivo would be of immense value in both drug discovery and routine …

[HTML][HTML] Proapoptotic Bcl-2 inhibitor as host directed therapy for pulmonary tuberculosis

S Jain, M Singh, M Sarhan, N Damiba… - Research …, 2024 - pmc.ncbi.nlm.nih.gov
Mycobacterium tuberculosis establishes within host cells by inducing anti-apoptotic Bcl-2
family proteins, triggering necrosis, inflammation, and fibrosis. Here, we demonstrate that …

[PDF][PDF] Sanjay K Jain, Savvas Andronikou, Pierre Goussard, Sameer Antani, David Gomez-Pastrana, Christophe Delacourt, Jeffrey R Starke

AA Ordonez, P Jean-Philippe, RS Browning… - neoplasia, 2020 - academia.edu
Tuberculosis is the leading cause of death globally that is due to a single pathogen, and up
to a fifth of patients with tuberculosis in high-incidence countries are children younger than …