[HTML][HTML] MicroRNAs as prognostic biomarkers for (cancer–associated) venous thromboembolism

RJS Anijs, YN Nguyen, SC Cannegieter… - Journal of Thrombosis …, 2023 - Elsevier
MicroRNAs (miRNAs) are small noncoding RNAs with gene regulatory functions and are
commonly dysregulated in disease states. As miRNAs are relatively stable, easily measured …

The role of tissue factor in signaling pathways of pathological conditions and angiogenesis

Z Heidari, Y Naeimzadeh, J Fallahi… - Current Molecular …, 2024 - benthamdirect.com
Tissue factor (TF) is an integral transmembrane protein associated with the extrinsic
coagulation pathway. TF gene expression is regulated in response to inflammatory …

The role of miRNAs in regulation of platelet activity and related diseases-a bioinformatic analysis

Z Wicik, P Czajka, C Eyileten, A Fitas, M Wolska… - Platelets, 2022 - Taylor & Francis
MicroRNAs (miRNAs) are small, non-coding RNAs, able to regulate cellular functions by
induction of mRNA degradation and post-transcriptional repression of gene expression …

Post-transcriptional control of haemostatic genes: mechanisms and emerging therapeutic concepts in thrombo-inflammatory disorders

S Danckwardt, DA Trégouët… - Cardiovascular …, 2023 - academic.oup.com
The haemostatic system is pivotal to maintaining vascular integrity. Multiple components
involved in blood coagulation have central functions in inflammation and immunity. A …

PBMC MicroRNAs: Promising biomarkers for the differential diagnosis of COVID-19 patients with abnormal coagulation indices

AKA Kasho, JS Nahand, A Salmaninejad, H Mirzaei… - Current …, 2023 - Springer
MicroRNAs, or miRNAs, may involve in coagulation and inflammation pathways caused by
severe Coronavirus disease (COVID-19). Accordingly, this attempt was made to explore the …

Evaluation of MicroRNA Expression Pattern (miR-28, miR-181a, miR-34a, and miR-31) in patients with COVID-19 admitted to ICU and diabetic COVID-19 patients

AR Khatami, M Taghizadieh, J Sadri Nahand… - Intervirology, 2023 - karger.com
Introduction: MicroRNAs, or miRNAs, with regulatory performance in inflammatory
responses and infection are the prevalent manifestations of severe coronavirus disease …

Dysregulated miRNAs network in the critical COVID-19: An important clue for uncontrolled immunothrombosis/thromboinflammation

SS Mortazavi-Jahromi, M Aslani - International Immunopharmacology, 2022 - Elsevier
Known as a pivotal immunohemostatic response, immunothrombosis is activated to restrict
the diffusion of pathogens. This beneficial intravascular defensive mechanism represents …

Circulating microRNAs targeting coagulation and fibrinolysis in patients with severe COVID-19

TA Helin, M Lemponen, K Immonen, P Lakkisto… - Thrombosis …, 2024 - Springer
Abstract Background Coronavirus-19 disease (COVID-19) frequently causes coagulation
disturbances. Data remains limited on the effects of microRNAs (miRNAs) on coagulation …

A transcriptome analysis of basal and stimulated VWF release from endothelial cells derived from patients with type 1 VWD

R Kloosterman, M Zago-Schmitt, J Grabell… - Blood …, 2023 - ashpublications.org
Type 1 von Willebrand disease (VWD) is associated with a reduction in qualitatively normal
von Willebrand factor (VWF). Current diagnostic guidelines only take into consideration the …

Endothelial dysfunction and atherosclerosis related miRNA‐expression in patients with haemophilia

S Noone, R Schubert, S Fichtlscherer, T Hilberg… - …, 2023 - Wiley Online Library
Introduction Elevated markers of endothelial dysfunction and inflammation indicate worse
endothelial function in the aging haemophilia population. MicroRNAs (miRNAs) regulate …