Advances in platelet function testing—light transmission aggregometry and beyond

J Le Blanc, F Mullier, C Vayne… - Journal of clinical …, 2020 - mdpi.com
Platelet function testing is essential for the diagnosis of hemostasis disorders. While there
are many methods used to test platelet function for research purposes, standardization is …

Sex-related differences in platelet aggregation: a literature review supplemented with local data from a group of generally healthy individuals

A Carazo, M Hrubša, L Konečný… - … in Thrombosis and …, 2023 - thieme-connect.com
The process of platelet aggregation is often influenced by several factors including sex and
age. A literature review confirmed the existence of sex-related differences in platelet …

Association of mean platelet volume with DSM-IV major depression in a large community-based population: the MELEN study

F Canan, S Dikici, A Kutlucan, G Celbek… - Journal of psychiatric …, 2012 - Elsevier
The relationship between major depression and increased platelet activity has been
previously stated by several studies. This study sought to test the relationship between mean …

Reference intervals for platelet aggregation assessed by multiple electrode platelet aggregometry

P Rubak, K Villadsen, AM Hvas - Thrombosis research, 2012 - Elsevier
INTRODUCTION: Analyses of platelet aggregation in hirudin whole blood using Multiplate®
was validated. Reference intervals for the most commonly used agonists were established …

Influence of sex on platelet reactivity in response to aspirin

KA Friede, MM Infeld, RS Tan… - Journal of the …, 2020 - Am Heart Assoc
Background There are sex differences in the efficacy and safety of aspirin for the prevention
of myocardial infarction and stroke. Whether this is explained by underlying differences in …

Sources of variability in platelet accumulation on type 1 fibrillar collagen in microfluidic flow assays

KB Neeves, AA Onasoga, RR Hansen, JJ Lilly… - PloS one, 2013 - journals.plos.org
Microfluidic flow assays (MFA) that measure shear dependent platelet function have
potential clinical applications in the diagnosis and treatment of bleeding and thrombotic …

Preclinical models in the study of sex differences

M Buoncervello, M Marconi, A Carè, P Piscopo… - Clinical …, 2017 - portlandpress.com
The biology of sex differences deals with the study of the disparities between females and
males and the related biological mechanisms. Gender medicine focuses on the impact of …

Sex-specific acute cerebrovascular responses to photothrombotic stroke in Mice

J Raman-Nair, G Cron, K MacLeod, B Lacoste - eneuro, 2024 - eneuro.org
Mechanisms underlying cerebrovascular stroke outcomes are poorly understood, and the
effects of biological sex on cerebrovascular regulation post-stroke have yet to be fully …

Effect of a single aspirin dose prior to fecal immunochemical testing on test sensitivity for detecting advanced colorectal neoplasms: a randomized clinical trial

H Brenner, S Calderazzo, T Seufferlein, L Ludwig… - Jama, 2019 - jamanetwork.com
Importance Fecal immunochemical tests for hemoglobin are widely used for colorectal
cancer (CRC) screening. Observational studies suggested that sensitivity of fecal …

A comprehensive study of ovine haemostasis to assess suitability to model human coagulation

SR Foley, C Solano, G Simonova, MM Spanevello… - Thrombosis research, 2014 - Elsevier
Introduction Similarities in size, anatomy and physiology have supported the use of sheep to
model a wide range of human diseases, including coagulopathy. However, coagulation …