Extrahepatic manifestations of chronic hepatitis C virus infection

P Cacoub, C Comarmond, F Domont… - Therapeutic …, 2016 - journals.sagepub.com
During hepatitis C virus (HCV) chronic infection, extrahepatic manifestations are frequent
and polymorphous. This article reports on a large cohort of patients with HCV-related …

The cryoglobulinaemias

M Ramos-Casals, JH Stone, MC Cid, X Bosch - The Lancet, 2012 - thelancet.com
Cryoglobulins are immunoglobulins that precipitate in vitro at temperatures less than 37° C
and produce organ damage through two main pathways: vascular sludging (hyperviscosity …

Regulatory T-cell responses to low-dose interleukin-2 in HCV-induced vasculitis

D Saadoun, M Rosenzwajg, F Joly, A Six… - … England Journal of …, 2011 - Mass Medical Soc
Background Patients with vasculitis induced by the hepatitis C virus (HCV) have reduced
levels of regulatory T cells (Tregs). Resolution of HCV infection correlates with cure of …

Cryoglobulinemia vasculitis

P Cacoub, C Comarmond, F Domont, L Savey… - The American journal of …, 2015 - Elsevier
Cryoglobulinemic vasculitis (CryoVas) is a small-vessel vasculitis involving mainly the skin,
the joints, the peripheral nervous system, and the kidneys. Type I CryoVas is single …

[PDF][PDF] Treatment of hepatitis C virus–associated mixed cryoglobulinemia with direct‐acting antiviral agents

ME Sise, AK Bloom, J Wisocky, MV Lin… - …, 2016 - Wiley Online Library
Hepatitis C virus (HCV) is the most common cause of mixed cryoglobulinemia syndrome
(MCS). The efficacy and safety of all‐oral direct‐acting antiviral (DAA) therapy in HCV …

How I treat monoclonal gammopathy of renal significance (MGRS)

JP Fermand, F Bridoux, RA Kyle… - Blood, The Journal …, 2013 - ashpublications.org
Recently, the term monoclonal gammopathy of renal significance (MGRS) was introduced to
distinguish monoclonal gammopathies that result in the development of kidney disease from …

A randomized controlled trial of rituximab for the treatment of severe cryoglobulinemic vasculitis

S De Vita, L Quartuccio, M Isola… - Arthritis & …, 2012 - Wiley Online Library
Objective To conduct a long‐term, prospective, randomized controlled trial evaluating
rituximab (RTX) therapy for severe mixed cryoglobulinemia or cryoglobulinemic vasculitis …

[HTML][HTML] Extrahepatic manifestations of chronic hepatitis C virus infection

P Cacoub, L Gragnani, C Comarmond… - Digestive and Liver …, 2014 - Elsevier
Hepatitis C virus (HCV) infected patients are known to be at risk of developing liver
complications ie cirrhosis and liver cancer. However, the risks of morbidity and mortality are …

Interferon-free antiviral treatment in B-cell lymphoproliferative disorders associated with hepatitis C virus infection

L Arcaini, C Besson, M Frigeni… - Blood, The Journal …, 2016 - ashpublications.org
Regression of hepatitis C virus (HCV)–associated lymphoma with interferon (IFN)-based
antiviral treatment supports an etiological link between lymphoma and HCV infection. In …

Sofosbuvir plus ribavirin for hepatitis C virus-associated cryoglobulinaemia vasculitis: VASCUVALDIC study

D Saadoun, V Thibault, SNS Ahmed, L Alric… - Annals of the …, 2016 - ard.bmj.com
Background Hepatitis C virus (HCV) is the aetiological agent for most cases of
cryoglobulinaemia vasculitis. Interferon-containing regimens are associated with important …