Compartmentalization of Mammalian folate-mediated one-carbon metabolism

AS Tibbetts, DR Appling - Annual review of nutrition, 2010 - annualreviews.org
The recognition that mitochondria participate in folate-mediated one-carbon metabolism
grew out of pioneering work beginning in the 1950s from the laboratories of DM Greenberg …

Choline transport for phospholipid synthesis

V Michel, Z Yuan, S Ramsubir… - … biology and medicine, 2006 - journals.sagepub.com
Choline is an essential nutrient for all cells because it plays a role in the synthesis of the
membrane phospholipid components of the cell membranes, as a methyl-group donor in …

Formation and regulation of mitochondrial membranes

LC Schenkel, M Bakovic - International journal of cell biology, 2014 - Wiley Online Library
Mitochondrial membrane phospholipids are essential for the mitochondrial architecture, the
activity of respiratory proteins, and the transport of proteins into the mitochondria. The …

Phosphocholine as a biomarker of breast cancer: molecular and biochemical studies

G Eliyahu, T Kreizman, H Degani - International journal of …, 2007 - Wiley Online Library
The discovery of metabolic and molecular markers that help improving the detection and
diagnosis of breast cancer is an important goal to be achieved. A high composite‐choline …

Choline transport links macrophage phospholipid metabolism and inflammation

SA Snider, KD Margison, P Ghorbani… - Journal of Biological …, 2018 - ASBMB
Choline is an essential nutrient that is required for synthesis of the main eukaryote
phospholipid, phosphatidylcholine. Macrophages are innate immune cells that survey and …

Potential roles of Toxocara canis larval excretory secretory molecules in immunomodulation and immune evasion

IF Abou-El-Naga, NMFH Mogahed - Acta Tropica, 2023 - Elsevier
Toxocara canis larvae invade various tissues of different vertebrate species without
developing into adults in paratenic host. The long-term survival of the larvae despite …

The choline transporter-like family SLC44: properties and roles in human diseases

E Traiffort, S O'Regan, M Ruat - Molecular aspects of medicine, 2013 - Elsevier
The Na+-independent, high affinity choline carrier system proposed to supply choline for the
synthesis of cell membrane phospholipids was recently associated with SLC44 family …

Choline kinase alpha—Putting the ChoK-hold on tumor metabolism

SP Arlauckas, AV Popov, EJ Delikatny - Progress in Lipid Research, 2016 - Elsevier
It is well established that lipid metabolism is drastically altered during tumor development
and response to therapy. Choline kinase alpha (ChoKα) is a key mediator of these changes …

CHOLINE TRANSPORTER-LIKE1 is required for sieve plate development to mediate long-distance cell-to-cell communication

J Dettmer, R Ursache, A Campilho, S Miyashima… - Nature …, 2014 - nature.com
Phloem, a plant tissue responsible for long-distance molecular transport, harbours specific
junctions, sieve areas, between the conducting cells. To date, little is known about the …

Choline transport for phospholipid synthesis: An emerging role of choline transporter-like protein 1

V Hedtke, M Bakovic - Experimental Biology and Medicine, 2019 - journals.sagepub.com
This review provides a summary of recent discoveries in choline transport and the proteins
mediating it with a specific focus on the choline transporter-like proteins (CTL)/solute carriers …