Neuroprotective mechanisms of resveratrol in Alzheimer's disease: role of SIRT1

BAQ Gomes, JPB Silva, CFR Romeiro… - Oxidative medicine …, 2018 - Wiley Online Library
Alzheimer's disease (AD) is a progressive and neurodegenerative disorder of the cortex and
hippocampus, which eventually leads to cognitive impairment. Although the etiology of AD …

Current approaches in lipid-based nanocarriers for oral drug delivery

M Plaza-Oliver, MJ Santander-Ortega… - Drug Delivery and …, 2021 - Springer
Lipid-based nanocarriers have gained much interest as carriers of drugs with poor oral
bioavailability because of their remarkable advantages like low toxicity, affordable scale-up …

Anti-inflammatory effects of resveratrol: Mechanistic insights

D de Sá Coutinho, MT Pacheco, RL Frozza… - International journal of …, 2018 - mdpi.com
Inflammation is the principal response invoked by the body to address injuries. Despite
inflammation constituting a crucial component of tissue repair, it is well known that …

[HTML][HTML] Resveratrol: From enhanced biosynthesis and bioavailability to multitargeting chronic diseases

N Pannu, A Bhatnagar - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Resveratrol, a phytoalexin with a wide range of pharmacological properties is synthesised
by plants in response to stress, injury, infection or UV radiations. As it is a secondary …

Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals

S Wang, R Su, S Nie, M Sun, J Zhang, D Wu… - The Journal of nutritional …, 2014 - Elsevier
Nanotechnology is an innovative approach that has potential applications in nutraceutical
research. Phytochemicals have promising potential for maintaining and promoting health, as …

Nanodelivery of natural antioxidants: an anti-aging perspective

A Vaiserman, A Koliada, A Zayachkivska… - … in bioengineering and …, 2020 - frontiersin.org
The aging process is known to be associated with heightened oxidative stress and related
systemic inflammation. Therefore, antioxidant supplementation is regarded as a promising …

Resveratrol and neuroprotection: impact and its therapeutic potential in Alzheimer's disease

MH Rahman, R Akter, T Bhattacharya… - Frontiers in …, 2020 - frontiersin.org
Alzheimer's disease (AD) is a progressive cortex and hippocampal neurodegenerative
disease which ultimately causes cognitively impaired decline in patients. The AD pathogen …

Resveratrol and neuroprotection: an insight into prospective therapeutic approaches against Alzheimer's disease from bench to bedside

F Islam, MH Nafady, MR Islam, S Saha, S Rashid… - Molecular …, 2022 - Springer
Alzheimer's disease (AD) is the most common cause of dementia and cognitive impairment;
yet, there is currently no treatment. A buildup of Aβ, tau protein phosphorylation, oxidative …

Administration of resveratrol: what formulation solutions to bioavailability limitations?

A Amri, JC Chaumeil, S Sfar, C Charrueau - Journal of controlled release, 2012 - Elsevier
Resveratrol (3, 5, 4′-trihydroxystilbene), a naturally occurring polyphenol, has attracted
considerable interest for its beneficial potentials for human health, which include anti …

Polyphenols: multipotent therapeutic agents in neurodegenerative diseases

KS Bhullar, HPV Rupasinghe - Oxidative medicine and cellular …, 2013 - Wiley Online Library
Aging leads to numerous transitions in brain physiology including synaptic dysfunction and
disturbances in cognition and memory. With a few clinically relevant drugs, a substantial …