Myelin in Alzheimer's disease: culprit or bystander?

M Maitre, H Jeltsch-David, NG Okechukwu… - Acta Neuropathologica …, 2023 - Springer
Alzheimer's disease (AD) is a neurodegenerative disorder with neuronal and synaptic
losses due to the accumulation of toxic amyloid β (Αβ) peptide oligomers, plaques, and …

Automated three-dimensional major white matter bundle segmentation using diffusion magnetic resonance imaging

C Andica, K Kamagata, S Aoki - Anatomical Science International, 2023 - Springer
White matter bundle segmentation using diffusion magnetic resonance imaging fiber
tractography enables detailed evaluation of individual white matter tracts three …

An anomaly detection approach to identify chronic brain infarcts on MRI

KM Van Hespen, JJM Zwanenburg, JW Dankbaar… - Scientific Reports, 2021 - nature.com
The performance of current machine learning methods to detect heterogeneous pathology is
limited by the quantity and quality of pathology in medical images. A possible solution is …

Microstructural disruption of the right inferior fronto‐occipital and inferior longitudinal fasciculus contributes to WMH‐related cognitive impairment

HF Chen, LL Huang, HY Li, Y Qian… - CNS Neuroscience …, 2020 - Wiley Online Library
Aims White matter hyperintensity (WMH) is the most common neuroimaging manifestation of
cerebral small vessel disease and is related to cognitive dysfunction or dementia. This study …

Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer's disease

A Pichet Binette, G Theaud, F Rheault, M Roy… - Elife, 2021 - elifesciences.org
Beta-amyloid (Aβ) and tau proteins, the pathological hallmarks of Alzheimer's disease (AD),
are believed to spread through connected regions of the brain. Combining diffusion imaging …

White matter microstructure alterations in type 2 diabetes mellitus and its correlation with cerebral small vessel disease and cognitive performance

Y Liu, Y Jiang, W Du, B Gao, J Gao, S Hu, Q Song… - Scientific Reports, 2024 - nature.com
Microstructural abnormalities of white matter fiber tracts are considered as one of the
etiology of diabetes-induced neurological disorders. We explored the cerebral white matter …

Altered white matter connectivity of ventral language networks in autism spectrum disorder: An automated fiber quantification analysis with multi-site datasets

M Li, M Izumoto, Y Wang, Y Kato, Y Iwatani, I Hirata… - Neuroimage, 2024 - Elsevier
Comprehension and pragmatic deficits are prevalent in autism spectrum disorder (ASD) and
are potentially linked to altered connectivity in the ventral language networks. However …

Alterations in white matter fiber tracts characterized by automated fiber-tract quantification and their correlations with cognitive impairment in neuromyelitis optica …

Z Yan, X Wang, Q Zhu, Z Shi, X Chen, Y Han… - Frontiers in …, 2022 - frontiersin.org
Objectives To investigate whether patients with neuromyelitis optica spectrum disorder
(NMOSD) have tract-specific alterations in the white matter (WM) and the correlations …

Early segmental white matter fascicle microstructural damage predicts the corresponding cognitive domain impairment in cerebral small vessel disease patients by …

L Huang, X Chen, W Sun, H Chen, Q Ye… - Frontiers in aging …, 2021 - frontiersin.org
Objective: To characterize earlier damage pattern of white matter (WM) microstructure in
cerebral small vessel disease (CSVD) and its relationship with cognitive domain …

Segmental disturbance of white matter microstructure in predicting mild cognitive impairment in idiopathic Parkinson's disease: An individualized study based on …

Z Yu, H Pang, H Yu, Z Wu, Z Ding, G Fan - Parkinsonism & Related …, 2023 - Elsevier
Purpose The neurobiological mechanisms and an early identification of MCI in idiopathic
Parkinson's disease (IPD) remain unclear. To investigate the abnormalities of types of white …