In the initiation of innate immune responses against pathogens, pattern-recognition
receptors (PRRs) have an essential role in recognizing specific components of …

Since the first attempt to administer insulin orally in humans more than 90 years ago, the oral
delivery of macromolecular drugs (> 1000 g/mol) has been rather disappointing. Although …

The Toll-like receptors (TLRs) and complement are key innate defense systems that are
triggered rapidly upon infection. Although both systems have been investigated primarily as …

Uncontrolled complement activation can induce many inflammatory and life threatening
conditions. Accordingly, the role of complement in initiation of adverse reactions to polymers …

Nanoparticles with surface projected polyethyleneoxide (PEO) chains in “mushroom− brush”
and “brush” configurations display stealth properties in systemic circulation and have …

Innate immunity is fundamental to our defense against microorganisms. Physiologically, the
intravascular innate immune system acts as a purging system that identifies and removes …

Complement and Toll‐like receptors (TLR s) play key roles in the host immune response
and are swiftly activated by infection or other types of immunological stress. This review …

Since the publication of the original review of piezoelectric acoustic sensors in this series
there has been a consistent, gradual expansion in the number of published papers using …

Two central pathways of innate immunity, complement and Toll-like receptors (TLRs), play
an important role in the pathogenesis of renal injury inherent to kidney transplantation …

Single-stranded oligonucleotides (ON) comprise a promising therapeutic platform that
enables selective modulation of currently undruggable targets. The development of novel …