Primary benign tumors of the spinal canal

JA Carlos-Escalante, ÁA Paz-López, B Cacho-Díaz… - World neurosurgery, 2022 - Elsevier
Benign tumors that grow in the spinal canal are heterogeneous neoplasms with low
incidence; from these, meningiomas and nerve sheath tumors (neurofibromas and …

Meningioma: Molecular Updates from the 2021 World Health Organization Classification of CNS Tumors and Imaging Correlates

N Soni, M Ora, G Bathla, D Szekeres, A Desai… - American Journal of …, 2024 - ajnr.org
Meningiomas, the most common primary intracranial neoplasms, account for more than one-
third of primary CNS tumors. While traditionally viewed as benign, meningiomas can be …

Proposal of a new grading system for meningioma resection: the Copenhagen Protocol

J Haslund-Vinding, J Skjoth-Rasmussen… - Acta …, 2022 - Springer
Introduction The extent of meningioma resection is the most fundamental risk factor for
recurrence, and exact knowledge of extent of resection is necessary for prognostication and …

Correlation of MTAP Immunohistochemistry With CDKN2A Status Assessed by Fluorescence In Situ Hybridization and Clinicopathological Features in CNS WHO …

S Sasaki, M Takeda, T Hirose, T Fujii… - … of Neuropathology & …, 2022 - academic.oup.com
CDKN2A homozygous deletion has occasionally been reported in atypical and anaplastic
meningiomas and is considered as one of the genetic alterations commonly involved in their …

Diagnostic and therapeutic strategy in anaplastic (malignant) meningioma, CNS WHO grade 3

V Di Nunno, C Giannini, S Asioli, A Conti, J Furtner… - Cancers, 2022 - mdpi.com
Simple Summary Only 1% of all meningioma diagnosis is classified as malignant
(anaplastic) meningioma. Due to their rarity, clinical management of these tumors presents …

Gene expression analysis during progression of malignant meningioma compared to benign meningioma

AD Maier, A Meddis, C Mirian, J Haslund-Vinding… - Journal of …, 2022 - thejns.org
OBJECTIVE Meningioma is the most common primary intracranial neoplasm. Only 1%–3%
of meningiomas are malignant according to the 2016 WHO criteria (WHO grade III). High …

WHO grade and pathological markers of meningiomas: clinical and prognostic role

RA Franca, R Della Monica, S Corvino… - … -Research and Practice, 2023 - Elsevier
In recent years, WHO grading criteria have emerged as an inaccurate tool to correctly predict
the risk of progression/recurrence for meningioma patients. Therefore, great efforts were …

Molecular determinants of outcomes in meningiomas

J Lynes, G Flores-Milan, S Rubino, J Arrington… - Frontiers in …, 2022 - frontiersin.org
Meningiomas are the most common intracranial primary tumor in adults. Surgery is the
predominant therapeutic modality for symptomatic meningiomas. Although the majority of …

Meningioma grading beyond histopathology: relevance of epigenetic and genetic features to predict clinical outcome

E Marastoni, V Barresi - Cancers, 2023 - mdpi.com
Simple Summary Meningiomas are common tumors of the central nervous system. The
grading system established by the World Health Organization has recently included pTERT …

Advances in molecular biological and translational studies in World Health Organization grades 2 and 3 meningiomas: a literature review

A Okano, S Miyawaki, Y Teranishi, K Ohara… - Neurologia medico …, 2022 - jstage.jst.go.jp
Abstract The treatment of World Health Organization (WHO) grades 2 and 3 meningiomas
remains difficult and controversial. The pathogenesis of high-grade meningiomas was …