Osteoimmunology is an interdisciplinary research field focused on the molecular
understanding of the interplay between the immune and skeletal systems. Although …

TNFα is crucially involved in the pathogenesis and progression of atherosclerosis,
myocardial ischemia/reperfusion injury and heart failure. The formation and release of TNFα …

Maladaptive, non-resolving inflammation contributes to chronic inflammatory diseases such
as atherosclerosis. Because macrophages remove necrotic cells, defective macrophage …

Bone homeostasis requires a delicate balance between the activities of bone-resorbing
osteoclasts and bone-forming osteoblasts. Various molecules coordinate osteoclast function …

Human blood CD14+ monocytes are bone marrow–derived white blood cells that sense and
respond to pathogens. Although innate immune activation by RNA viruses preferentially …

Postmenopausal osteoporosis and rheumatoid joint destruction result from increased
osteoclast formation and bone resorption induced by receptor activator of NF-κB ligand …

TNFα is crucially involved in the pathogenesis and progression of myocardial
ischemia/reperfusion injury and heart failure. The formation and release of TNFα and its …

The polarization of macrophages is regulated by transcription factors, such as NF-κB and
activator protein 1 (AP-1). In this manuscript, we delineated the role of the transcription factor …

T cells play a critical role in tumor immunosurveillance by eliminating newly transformed
somatic cells. However, tumor cell variants can escape from immunological control after …

Doxorubicin (DOX) is a highly effective drug, but its cardiotoxicity restricts its therapeutic
index. Oxidative stress is the major etiopathological factor in DOX-induced cardiotoxicity …