Cancer heterogeneity, a hallmark enabling clonal survival and therapy resistance, is shaped
by active immune responses. Antigen-specific T cells can control cancer, as revealed …

Neuroinflammatory response is primarily a protective mechanism in the brain. However,
excessive and chronic inflammatory responses can lead to deleterious effects involving …

These parameters were developed by the Joint Task Force on Practice Parameters (JTFPP),
representing the American Academy of Allergy, Asthma & Immunology (AAAAI); the …

Endometrial polyps are overgrowths of endometrial glands that typically protrude into the
uterine cavity. Endometrial polyps are benign in nature and affect both reproductive age and …

Mast cells can function as effector and immunoregulatory cells in immunoglobulin E–
associated allergic disorders, as well as in certain innate and adaptive immune responses …

Cathelicidins, like other antimicrobial peptides, exhibit direct antimicrobial activities against
a broad spectrum of microbes, including both Gram-positive and Gram-negative bacteria …

Mast cells play as the major effector cells in immediate hypersensitivity through activation via
the high-affinity IgE receptor, FcɛRI, although many other functions have recently been …

Mast cells are classically viewed as effector cells of IgE-mediated allergic diseases.
However, over the last decade our understanding has been enriched about their roles in …

Mast cells are multifunctional cells that initiate not only IgE-dependent allergic diseases but
also play a fundamental role in innate and adaptive immune responses to microbial …

Accumulation of mast cells (MCs) in tumours was described by Ehrlich in his doctoral thesis.
Since this early account, ample evidence has been provided highlighting participation of …