Targeting autophagy to overcome drug resistance: further developments

H Chang, Z Zou - Journal of hematology & oncology, 2020 - Springer
Inhibiting cell survival and inducing cell death are the main approaches of tumor therapy.
Autophagy plays an important role on intracellular metabolic homeostasis by eliminating …

Crosstalks between inflammasome and autophagy in cancer

C Chung, W Seo, P Silwal, EK Jo - Journal of hematology & oncology, 2020 - Springer
Both inflammasomes and autophagy have important roles in the intracellular homeostasis,
inflammation, and pathology; the dysregulation of these processes is often associated with …

Competitive glucose metabolism as a target to boost bladder cancer immunotherapy

J Afonso, LL Santos, A Longatto-Filho… - Nature Reviews …, 2020 - nature.com
Bladder cancer—the tenth most frequent cancer worldwide—has a heterogeneous natural
history and clinical behaviour. The predominant histological subtype, urothelial bladder …

Path of Silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance

HS Tuli, S Mittal, D Aggarwal, G Parashar… - Seminars in Cancer …, 2021 - Elsevier
In the last few decades, targeting cancer by the use of dietary phytochemicals has gained
enormous attention. The plausible reason and believe or mind set behind this fact is …

Silymarin and cancer: A dual strategy in both in chemoprevention and chemosensitivity

D Delmas, J Xiao, A Vejux, V Aires - Molecules, 2020 - mdpi.com
Silymarin extracted from milk thistle consisting of flavonolignan silybin has shown
chemopreventive and chemosensitizing activity against various cancers. The present review …

The various regulatory functions of long noncoding RNAs in apoptosis, cell cycle, and cellular senescence

M Heydarnezhad Asl… - Journal of cellular …, 2022 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are a group of noncoding cellular RNAs involved in
significant biological phenomena such as differentiation, cell development, genomic …

Phytochemicals as a complement to cancer chemotherapy: pharmacological modulation of the autophagy-apoptosis pathway

MA Rahman, MA Hannan, R Dash… - Frontiers in …, 2021 - frontiersin.org
Bioactive plant derived compounds are important for a wide range of therapeutic
applications, and some display promising anticancer properties. Further evidence suggests …

Molecular beacon strategies for sensing purpose

N Bidar, M Amini, F Oroojalian, B Baradaran… - TrAC Trends in …, 2021 - Elsevier
The improvement of nucleic acid probes as vital molecular engineering devices will cause a
noteworthy contribution to developments in bioimaging, biosensing, and disorders …

Metabolism, transport and drug–drug interactions of silymarin

Y Xie, D Zhang, J Zhang, J Yuan - Molecules, 2019 - mdpi.com
Silymarin, the extract of milk thistle, and its major active flavonolignan silybin, are common
products widely used in the phytotherapy of liver diseases. They also have promising effects …

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

SZ Bahojb Mahdavi, A Jebelli… - Medicinal research …, 2024 - Wiley Online Library
Infections caused by viruses as the smallest infectious agents, pose a major threat to global
public health. Viral infections utilize different host mechanisms to facilitate their own …