Extending the Potency and Lifespan of Antibiotics: Inhibitors of Gram-Negative Bacterial Efflux Pumps

M Duffey, RP Jumde, RMA da Costa… - ACS Infectious …, 2024 - ACS Publications
Efflux is a natural process found in all prokaryotic and eukaryotic cells that removes a
diverse range of substrates from inside to outside. Many antibiotics are substrates of …

Design, synthesis and bioactivity studies of novel triazolopyrimidinone compounds.

H ISTANBULLU, G BAYRAKTAR… - Journal of Research …, 2022 - search.ebscohost.com
This study was aimed to develop novel compounds to combat antimicrobial resistance,
which is one of the biggest threats to global health. For this purpose, compounds bearing …