Surgery and drug therapy are the two principal options for cancer treatment. However, their
clinical benefits are hindered by the difficulty of accurate location of the tumors and timely …

Fluorescence-guided surgery is an intraoperative optical imaging method that provides
surgeons with real-time guidance for the delineation of tumours. Currently, in phase 1 and 2 …

The incidence of oesophageal adenocarcinoma (EAC) is steeply rising. Early lesion
detection is a critical factor for improving disease prognosis. We developed and investigated …

Molecular imaging is an emerging strategy for in vivo visualization of cancer over time based
on biological mechanisms of disease activity. Optical imaging methods offer a number of …

Clinical workflows for the non-invasive detection and characterization of disease states
could benefit from optical-imaging biomarkers. In this Perspective, we discuss opportunities …

In the last two decades, the application of surface enhanced Raman scattering (SERS)
nanoparticles for preclinical cancer imaging has attracted increasing attention. Raman …

The advent of fluorescence imaging (FI) for cancer cell detection in the field of oncology is
promising for both cancer screening and surgical resection. Particularly, FI in cancer …

Background & Aims Many cancers in the proximal colon develop via from sessile serrated
adenomas (SSAs), which have flat, subtle features that are difficult to detect with …

Flexible high-definition white-light endoscopy is the current gold standard in screening for
cancer and its precursor lesions in the gastrointestinal tract. However, miss rates are high …

We report the development, characterization, and validation of a peptide specific for the
extracellular domain of HER2. This probe chemistry was developed for molecular imaging …