CNS targeting AAV vectors and methods of use thereof
The invention in some aspects relates to recombinant adeno-associated viruses useful for
targeting transgenes to CNS tissue, and compositions comprising the same, and methods of …
targeting transgenes to CNS tissue, and compositions comprising the same, and methods of …
Method of increasing the function of an AAV vector
L Vandenberghe, G Gao, JM Wilson - US Patent 8,999,678, 2015 - Google Patents
The present invention provides a method of improving vectors derived from AAV which are
non-functional and/or which perform weakly. In one aspect, the method provides a method …
non-functional and/or which perform weakly. In one aspect, the method provides a method …
Method of detecting and/or identifying adeno-associated virus (AAV) sequences and isolating novel sequences identified thereby
G Gao, J Wilson, M Alvira - US Patent App. 10/291,583, 2003 - Google Patents
US20030138772A1 - Method of detecting and/or identifying adeno-associated virus (AAV)
sequences and isolating novel sequences identified thereby - Google Patents US20030138772A1 …
sequences and isolating novel sequences identified thereby - Google Patents US20030138772A1 …
AAV capsid library and AAV capsid proteins
5,993,800 A 1 1/1999 Linsley et al. 6,491,907 B1* 12/2002 Rabinowitz et al......... 424.93. 2
6,936,243 B2 8/2005 Snyder et al. 6,943,012 B2 9, 2005 Ehrhardt et al. 7,060,497 B2 6 …
6,936,243 B2 8/2005 Snyder et al. 6,943,012 B2 9, 2005 Ehrhardt et al. 7,060,497 B2 6 …
Method for detecting adeno-associated virus
G Gao, JM Wilson, MR Alvira - US Patent 8,524,446, 2013 - Google Patents
First worldwide family litigation filed litigation Critical https://patents. darts-ip. com/? family=
27502639&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
27502639&utm_source= google_patent&utm_medium= platform_link&utm_campaign …
CNS targeting AAV vectors and methods of use thereof
US9701984B2 - CNS targeting AAV vectors and methods of use thereof - Google Patents
US9701984B2 - CNS targeting AAV vectors and methods of use thereof - Google Patents CNS …
US9701984B2 - CNS targeting AAV vectors and methods of use thereof - Google Patents CNS …
Compositions and methods for altering tissue specificity and improving AAV9-mediated gene transfer
JM Wilson, CL Bell, LH Vandenberghe - US Patent 9,884,071, 2018 - Google Patents
A method of altering the targeting and/or cellular uptake efficiency of an adeno-associated
virus (AAV) viral vector having a capsid containing an AAVO cell surface binding domain is …
virus (AAV) viral vector having a capsid containing an AAVO cell surface binding domain is …
Isolation of novel AAV'S and uses thereof
The invention in some aspects relates to isolated nucleic acids, compositions, and kits useful
for identifying adeno-associated viruses in cells. In some aspects, the invention provides kits …
for identifying adeno-associated viruses in cells. In some aspects, the invention provides kits …