Immunology of pediatric HIV infection

NH Tobin, GM Aldrovandi - Immunological reviews, 2013 - Wiley Online Library
Most infants born to human immunodeficiency virus (HIV)‐infected women escape HIV
infection. Infants evade infection despite an immature immune system and, in the case of …

[HTML][HTML] HIV in pregnancy: Mother-to-child transmission, pharmacotherapy, and toxicity

L Cerveny, P Murthi, F Staud - … et Biophysica Acta (BBA)-Molecular Basis of …, 2021 - Elsevier
An estimated 1.3 million pregnant women were living with HIV in 2018. HIV infection is
associated with adverse pregnancy outcomes and all HIV-positive pregnant women …

Paediatric HIV infection: the potential for cure

PJ Goulder, SR Lewin, EM Leitman - Nature Reviews Immunology, 2016 - nature.com
Recent anecdotal reports of HIV-infected children who received early antiretroviral therapy
(ART) and showed sustained control of viral replication even after ART discontinuation have …

Progress, challenges, and new opportunities for the prevention of mother-to-child transmission of HIV under the US President's Emergency Plan for AIDS Relief

BH Chi, MR Adler, O Bolu… - JAIDS Journal of …, 2012 - journals.lww.com
In June 2011, the Joint United Nations Programme on HIV/AIDS, the US President's
Emergency Plan for AIDS Relief (PEPFAR), and other collaborators outlined a …

The ontogeny and function of placental macrophages

JR Thomas, P Naidu, A Appios… - Frontiers in …, 2021 - frontiersin.org
The placenta is a fetal-derived organ whose function is crucial for both maternal and fetal
health. The human placenta contains a population of fetal macrophages termed Hofbauer …

Distinct functional programming of human fetal and adult monocytes

ER Krow-Lucal, CC Kim, TD Burt… - Blood, The Journal of …, 2014 - ashpublications.org
Preterm birth affects 1 out of 9 infants in the United States and is the leading cause of long-
term neurologic handicap and infant mortality, accounting for 35% of all infant deaths in …

Pregnancy and infant outcomes among women using the dapivirine vaginal ring in early pregnancy

B Makanani, JE Balkus, Y Jiao… - JAIDS Journal of …, 2018 - journals.lww.com
Background: Monthly use of the dapivirine vaginal ring has been shown to be safe and
effective for HIV-1 prevention in nonpregnant reproductive-aged women. The impact of …

Pregnant women's access to PMTCT and ART services in South Africa and implications for universal antiretroviral treatment

A Hussain, D Moodley, S Naidoo, TM Esterhuizen - PloS one, 2011 - journals.plos.org
Objectives We describe pregnant womens' access to PMTCT and HAART services and
associated birth outcomes in South Africa. Methods Women recuperating in postnatal wards …

Effect of natural and ARV-induced viral suppression and viral breakthrough on anti-HIV antibody proportion and avidity in patients with HIV-1 subtype B infection

SK Wendel, CE Mullis, SH Eshleman, JN Blankson… - PloS one, 2013 - journals.plos.org
Background Viral suppression and viral breakthrough impact the humoral immune response
to HIV infection. We evaluated the impact of viral suppression and viral breakthrough on …

Detection of acute and early HIV-1 infections in an HIV hyper-endemic area with limited resources

SH Mayaphi, DJ Martin, TC Quinn, O Laeyendecker… - PLoS …, 2016 - journals.plos.org
Background Two thirds of the world's new HIV infections are in sub-Saharan Africa. Acute
HIV infection (AHI) is the time of virus acquisition until the appearance of HIV antibodies …