Diabetes Mellitus (DM) is a complex metabolic disorder associated with multiple
microvascular complications leading to nephropathy, retinopathy, and neuropathy. Mounting …

Reactive oxygen species (ROS) are radical oxygen intermediates that serve as important
second messengers in signal transduction. However, when the accumulation of these …

The endothelium is a monocellular layer covering the inner surface of blood vessels. It
maintains vascular homeostasis regulating vascular tone and permeability and exerts anti …

More than 10% of the world's population already suffers from varying degrees of diabetes
mellitus (DM), but there is still no cure for the disease. Cardiovascular disease (CVD) is one …

The prevalence of diabetes mellitus (DM) is increasing at a staggering rate around the
world. In the United States, more than 30.3 million Americans have DM. Type 2 diabetes …

Background Patients with familial hypercholesterolemia (FH) display high levels of low‐
density lipoprotein cholesterol (LDL‐c), endothelial dysfunction, and increased risk of …

Red blood cells (RBCs) are suggested to play a role in cardiovascular regulation by
exporting nitric oxide (NO) bioactivity and ATP under hypoxia. It remains unknown whether …

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disease with still growing incidence
among adults and young people worldwide. Patients with T2DM are more susceptible to …

Exosomes are the smallest subset of extracellular signaling vesicles secreted by most cells
with the ability to communicate with other tissues and cell types over long distances. Their …

Whole-or partial-body exposure to ionizing radiation damages major organ systems, leading
to dysfunction on both acute and chronic timescales. Radiation medical countermeasures …