The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Psychiatric disorders are highly prevalent, often devastating diseases that negatively impact
the lives of millions of people worldwide. Although their etiological and diagnostic …

Dopamine is a neurotransmitter that plays a critical role both peripherally and centrally in
vital functions such as cognition, reward, satiety, voluntary motor movements, pleasure, and …

This paper discusses the current evidence from animal and human studies for a central role
of inflammation in schizophrenia. In animal models, pre-or perinatal elicitation of the immune …

Crosstalk between inflammatory pathways and neurocircuits in the brain can lead to
behavioural responses, such as avoidance and alarm, that are likely to have provided early …

Peripheral blood C-reactive protein (CRP) is a biomarker used clinically to measure
systemic inflammation and is reproducibly increased in a subset of patients with major …

Background: Studies investigating the impact of a variety of inflammatory stimuli on the brain
and behavior have reported evidence that inflammation and release of inflammatory …

Depression is associated with alterations in corticostriatal reward circuitry. One
pathophysiological pathway that may drive these changes is inflammation. Biomarkers of …

Psychiatric sequelae substantially contribute to the post-acute burden of disease associated
with COVID-19, persisting months after clearance of the virus. Brain imaging shows white …

Patients with ulcerative colitis (UC) have a high prevalence of mental disorders, such as
depression and anxiety. Gut microbiota imbalance and disturbed metabolism have been …