Cell division in apicomplexan parasites

ME Francia, B Striepen - Nature Reviews Microbiology, 2014 - nature.com
Toxoplasma gondii and Plasmodium falciparum are important human pathogens. These
parasites and many of their apicomplexan relatives undergo a complex developmental …

Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence

IJ Blader, JP Saeij - Apmis, 2009 - Wiley Online Library
Toxoplasma gondii is an obligate intracellular protozoan parasite that can infect most warm‐
blooded animals and cause severe and life‐threatening disease in developing fetuses and …

Toxoplasma gondii exploits the host ESCRT machinery for parasite uptake of host cytosolic proteins

Y Rivera-Cuevas, J Mayoral, M Di Cristina… - PLoS …, 2021 - journals.plos.org
Toxoplasma gondii is a master manipulator capable of effectively siphoning the resources
from the host cell for its intracellular subsistence. However, the molecular underpinnings of …

Dense granule biogenesis, secretion, and function in Toxoplasma gondii

MB Griffith, CS Pearce… - Journal of Eukaryotic …, 2022 - Wiley Online Library
Toxoplasma gondii is an obligate intracellular parasite and the causative agent of
Toxoplasmosis. A key to understanding and treating the disease lies with determining how …

Leading a sheltered life: intracellular pathogens and maintenance of vacuolar compartments

Y Kumar, RH Valdivia - Cell host & microbe, 2009 - cell.com
Many intracellular pathogens survive in vacuolar niches composed of host-derived
membranes modified extensively by pathogen proteins and lipids. Although intracellular …

The Apicomplexan Parasite Toxoplasma gondii

ILS Delgado, S Zúquete, D Santos, AP Basto, A Leitão… - Encyclopedia, 2022 - mdpi.com
Definition Toxoplasma gondii is a ubiquitous zoonotic parasite with an obligatory
intracellular lifestyle. It relies on a specialized set of cytoskeletal and secretory organelles for …

The parasite Toxoplasma sequesters diverse Rab host vesicles within an intravacuolar network

JD Romano, SJ Nolan, C Porter, K Ehrenman… - Journal of Cell …, 2017 - rupress.org
Many intracellular pathogens subvert host membrane trafficking pathways to promote their
replication. Toxoplasma multiplies in a membrane-bound parasitophorous vacuole (PV) that …

Toxoplasma Mechanisms for Delivery of Proteins and Uptake of Nutrients Across the Host-Pathogen Interface

Y Wang, LO Sangaré… - Annual review of …, 2020 - annualreviews.org
Many intracellular pathogens, including the protozoan parasite Toxoplasma gondii, live
inside a vacuole that resides in the host cytosol. Vacuolar residence provides these …

Toxoplasma gondii salvages sphingolipids from the host Golgi through the rerouting of selected Rab vesicles to the parasitophorous vacuole

JD Romano, S Sonda, E Bergbower… - Molecular biology of …, 2013 - Am Soc Cell Biol
The obligate intracellular protozoan Toxoplasma gondii actively invades mammalian cells
and, upon entry, forms its own membrane-bound compartment, named the parasitophorous …

Proximity-Labeling Reveals Novel Host and Parasite Proteins at the Toxoplasma Parasitophorous Vacuole Membrane

AM Cygan, PM Jean Beltran, AG Mendoza, TC Branon… - MBio, 2021 - Am Soc Microbiol
Toxoplasma gondii is a ubiquitous, intracellular parasite that envelops its parasitophorous
vacuole with a protein-laden membrane (PVM). The PVM is critical for interactions with the …