Hox clusters as models for vertebrate genome evolution

S Hoegg, A Meyer - Trends in genetics, 2005 - cell.com
The surprising variation in the number of Hox clusters and the genomic architecture within
vertebrate lineages, especially within the ray-finned fish, reflects a history of duplications …

The “fish-specific” Hox cluster duplication is coincident with the origin of teleosts

KD Crow, PF Stadler, VJ Lynch… - Molecular Biology …, 2006 - academic.oup.com
The Hox gene complement of zebrafish, medaka, and fugu differs from that of other
gnathostome vertebrates. These fishes have seven to eight Hox clusters compared to the …

Evolution of microRNAs located within Hox gene clusters

A Tanzer, CT Amemiya, CB Kim… - Journal of Experimental …, 2005 - Wiley Online Library
MicroRNAs (miRNAs) form an abundant class of non‐coding RNA genes that have an
important function in post‐transcriptional gene regulation and in particular modulate the …

[HTML][HTML] Kiwi genome provides insights into evolution of a nocturnal lifestyle

D Le Duc, G Renaud, A Krishnan, MS Almén, L Huynen… - Genome biology, 2015 - Springer
Background Kiwi, comprising five species from the genus Apteryx, are endangered, ground-
dwelling bird species endemic to New Zealand. They are the smallest and only nocturnal …

[HTML][HTML] Analyses of 5′ regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3)

V Bhatnagar, G Xu, BA Hamilton, DM Truong… - Journal of human …, 2006 - nature.com
Kidney excretion of numerous organic anionic drugs and endogenous metabolites is carried
out by a family of multispecific organic anion transporters (OATs). Two closely related …

Bichir HoxA cluster sequence reveals surprising trends in ray-finned fish genomic evolution

C Chiu, K Dewar, GP Wagner, K Takahashi… - Genome …, 2004 - genome.cshlp.org
The study of Hox clusters and genes provides insights into the evolution of genomic
regulation of development. Derived ray-finned fishes (Actinopterygii, Teleostei) such as …

[HTML][HTML] Comparative phylogenomic analyses of teleost fish Hox gene clusters: lessons from the cichlid fish Astatotilapia burtoni

S Hoegg, JL Boore, JV Kuehl, A Meyer - BMC genomics, 2007 - Springer
Background Teleost fish have seven paralogous clusters of Hox genes stemming from two
complete genome duplications early in vertebrate evolution, and an additional genome …

Highly conserved syntenic blocks at the vertebrate Hox loci and conserved regulatory elements within and outside Hox gene clusters

AP Lee, EGL Koh, A Tay, S Brenner… - Proceedings of the …, 2006 - National Acad Sciences
Hox genes in vertebrates are clustered, and the organization of the clusters has been highly
conserved during evolution. The conservation of Hox clusters has been attributed to …

[HTML][HTML] Origin and functional diversification of an amphibian defense peptide arsenal

K Roelants, BG Fry, L Ye, B Stijlemans, L Brys… - PLoS …, 2013 - journals.plos.org
The skin secretion of many amphibians contains an arsenal of bioactive molecules,
including hormone-like peptides (HLPs) acting as defense toxins against predators, and …

Complete HOX cluster characterization of the coelacanth provides further evidence for slow evolution of its genome

CT Amemiya, TP Powers… - Proceedings of the …, 2010 - National Acad Sciences
The living coelacanth is a lobe-finned fish that represents an early evolutionary departure
from the lineage that led to land vertebrates, and is of extreme interest scientifically. It has …