Cuproptosis was a copper-dependent and unique kind of cell death that was separate from
existing other forms of cell death. The last decade has witnessed a considerable increase in …

Copper (Cu) homeostasis is gaining increasing attention in human health as both Cu
overload and deficiency evokes pathological changes including cardiovascular diseases …

The presence of Akkermansia muciniphila (Akk) in the human gut is associated with good
health, leanness and fitness. Mouse experimentation has demonstrated positive effects for …

Copper, an essential trace element that exists in oxidized and reduced forms, has pivotal
roles in a variety of biological processes, including redox chemistry, enzymatic reactions …

Macroautophagy/autophagy is an evolutionally conserved catabolic process in which
cytosolic contents, such as aggregated proteins, dysfunctional organelle, or invading …

High incidences of morbidity and mortality associated with age-related diseases among the
elderly population are a socio-economic challenge. Aging is an irreversible and inevitable …

The sensu stricto autophagy, macroautophagy, is considered to be both a metabolic process
as well as a bona fide quality control process. The question as to how these two aspects of …

Caloric restriction (CR) mimetics are molecules that produce beneficial effects on health and
longevity in model organisms and humans, without the challenges of maintaining a CR diet …

Cuproptosis, a newly characterized form of regulated cell death driven by copper
accumulation, has emerged as a significant mechanism underlying various non-cancerous …

Aging is the subject of many studies, facilitating the discovery of many interventions.
Epigenetic influences numerous life processes by regulating gene expression and also …