High-throughput relative quantification of fatty acids by 12-plex isobaric labeling and microchip capillary electrophoresis-Mass spectrometry
Abstract Background Fatty acids (FAs) are essential cellular components and play important
roles in various biological processes. Importantly, FAs produced by microorganisms from …
roles in various biological processes. Importantly, FAs produced by microorganisms from …
Updates of the current strategies of labeling for N-glycan analysis
Y Helali, C Delporte - Journal of Chromatography B, 2024 - Elsevier
This mini review summarizes the current methods used for screening N-glycosylation of
glycoproteins, with a specific focus on therapeutic proteins and on techniques involving the …
glycoproteins, with a specific focus on therapeutic proteins and on techniques involving the …
6-Plex mdSUGAR Isobaric-Labeling Guide Fingerprint Embedding for Glycomics Analysis
Glycans are vital biomolecules with diverse functions in biological processes. Mass
spectrometry (MS) has become the most widely employed technology for glycomics studies …
spectrometry (MS) has become the most widely employed technology for glycomics studies …
Recent Advances in Labeling‐Based Quantitative Glycomics: From High‐Throughput Quantification to Structural Elucidation
Glycosylation, a crucial posttranslational modification (PTM), plays important roles in
numerous biological processes and is linked to various diseases. Despite its significance …
numerous biological processes and is linked to various diseases. Despite its significance …
Development of novel isobaric tags enables accurate and sensitive multiplexed proteomics using complementary ions
High-throughput quantitative analysis of the cells' proteomes across multiple conditions such
as various perturbations and different time points is essential for gaining insights into …
as various perturbations and different time points is essential for gaining insights into …
In-Membrane Enrichment and Peptic Digestion to Facilitate Analysis of Monoclonal Antibody Glycosylation
The number of therapeutic monoclonal antibodies (mAbs) is growing rapidly due to their
widespread use for treating various diseases and health conditions. Assessing the …
widespread use for treating various diseases and health conditions. Assessing the …
Rapid and Definitive Identification of Cyclic Peptide Soft Spots by Isotope-Labeled Reductive Dimethylation and Mass Spectrometry Fragmentation
Y Feng, A Qirjollari, MV Fawaz, MT Cancilla… - Analytical …, 2024 - ACS Publications
Cyclic peptides are an emerging therapeutic modality over the past few decades. To identify
drug candidates with sufficient proteolytic stability for oral administration, it is critical to …
drug candidates with sufficient proteolytic stability for oral administration, it is critical to …
Bidirectional Two-Sample Mendelian Randomization Study of Immunoglobulin G N-Glycosylation and Senescence-Associated Secretory Phenotype
H Wang, D Liu, X Meng, W Sun, C Li, H Lu… - International Journal of …, 2024 - mdpi.com
Observational studies revealed changes in Immunoglobulin G (IgG) N-glycosylation during
the aging process. However, it lacks causal insights and remains unclear in which direction …
the aging process. However, it lacks causal insights and remains unclear in which direction …
Second Special Issue on Methods for Omics Research: Proteome Research and Beyond
This Second Special Issue compiles 19 studies answering our open call to describe novel,
or at least significantly updated, Methods for Omics Research. The common thread among …
or at least significantly updated, Methods for Omics Research. The common thread among …
12-Plex Isobaric Multiplex Labeling Reagents for Carbonyl-Containing Compound (SUGAR) Tag-Enabled High-Throughput Quantitative Glycomics
Glycans, which are ubiquitously distributed on most proteins and cell surfaces, are a class of
important biomolecules playing crucial roles in various biological processes such as …
important biomolecules playing crucial roles in various biological processes such as …