The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle, structure and functions, and use as a potential target in the development of vaccines and …

W Wu, Y Cheng, H Zhou, C Sun, S Zhang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) continues to take a heavy toll on personal
health, healthcare systems, and economies around the globe. Scientists are expending …

SARS‐CoV‐2, the pandemic coronavirus: Molecular and structural insights

SB Kadam, GS Sukhramani, P Bishnoi… - Journal of basic …, 2021 - Wiley Online Library
The outbreak of a novel coronavirus associated with acute respiratory disease, called
COVID‐19, marked the introduction of the third spillover of an animal coronavirus (CoV) to …

Rapid detection of SARS-CoV-2 antigens using high-purity semiconducting single-walled carbon nanotube-based field-effect transistors

W Shao, MR Shurin, SE Wheeler, X He… - ACS applied materials & …, 2021 - ACS Publications
Early diagnosis of SARS-CoV-2 infection is critical for facilitating proper containment
procedures, and a rapid, sensitive antigen assay is a critical step in curbing the pandemic. In …

Structure and function of major SARS-CoV-2 and SARS-CoV proteins

R Gorkhali, P Koirala, S Rijal… - … and biology insights, 2021 - journals.sagepub.com
SARS-CoV-2 virus, the causative agent of COVID-19 pandemic, has a genomic organization
consisting of 16 nonstructural proteins (nsps), 4 structural proteins, and 9 accessory …

Performance of rapid antigen tests for COVID-19 diagnosis: a systematic review and meta-analysis

MF Khalid, K Selvam, AJN Jeffry, MF Salmi, MA Najib… - Diagnostics, 2022 - mdpi.com
The identification of viral RNA using reverse transcription quantitative polymerase chain
reaction (RT-qPCR) is the gold standard for identifying an infection caused by SARS-CoV-2 …

The coronavirus nucleocapsid is a multifunctional protein

R McBride, M Van Zyl, BC Fielding - Viruses, 2014 - mdpi.com
The coronavirus nucleocapsid (N) is a structural protein that forms complexes with genomic
RNA, interacts with the viral membrane protein during virion assembly and plays a critical …

The SARS coronavirus nucleocapsid protein–forms and functions

C Chang, MH Hou, CF Chang, CD Hsiao, T Huang - Antiviral research, 2014 - Elsevier
The nucleocapsid phosphoprotein of the severe acute respiratory syndrome coronavirus
(SARS-CoV N protein) packages the viral genome into a helical ribonucleocapsid (RNP) …

Computational inference of selection underlying the evolution of the novel coronavirus, severe acute respiratory syndrome coronavirus 2

R Cagliani, D Forni, M Clerici, M Sironi - Journal of virology, 2020 - Am Soc Microbiol
The novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that
recently emerged in China is thought to have a bat origin, as its closest known relative …

SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication

ZQ Zheng, SY Wang, ZS Xu, YZ Fu, YY Wang - Cell Discovery, 2021 - nature.com
The newly emerging coronavirus SARS-CoV-2 causes severe lung disease and substantial
mortality. How the virus evades host defense for efficient replication is not fully understood …

Human coronaviruses: viral and cellular factors involved in neuroinvasiveness and neuropathogenesis

M Desforges, A Le Coupanec, JK Stodola… - Virus research, 2014 - Elsevier
Among the various respiratory viruses infecting human beings, coronaviruses are important
pathogens, which usually infect the upper respiratory tract, where they are mainly associated …