Tissue engineering and regenerative medicine: achievements, future, and sustainability in Asia
F Han, J Wang, L Ding, Y Hu, W Li, Z Yuan… - … in bioengineering and …, 2020 - frontiersin.org
Exploring innovative solutions to improve the healthcare of the aging and diseased
population continues to be a global challenge. Among a number of strategies toward this …
population continues to be a global challenge. Among a number of strategies toward this …
Tendon and ligament healing and current approaches to tendon and ligament regeneration
NL Leong, JL Kator, TL Clemens… - Journal of …, 2020 - Wiley Online Library
Ligament and tendon injuries are common problems in orthopedics. There is a need for
treatments that can expedite nonoperative healing or improve the efficacy of surgical repair …
treatments that can expedite nonoperative healing or improve the efficacy of surgical repair …
Exosomes from embryonic mesenchymal stem cells alleviate osteoarthritis through balancing synthesis and degradation of cartilage extracellular matrix
Background Mesenchymal stem cell therapy for osteoarthritis (OA) has been widely
investigated, but the mechanisms are still unclear. Exosomes that serve as carriers of …
investigated, but the mechanisms are still unclear. Exosomes that serve as carriers of …
Current progress in tendon and ligament tissue engineering
WL Lim, LL Liau, MH Ng, SR Chowdhury… - Tissue engineering and …, 2019 - Springer
Background: Tendon and ligament injuries accounted for 30% of all musculoskeletal
consultations with 4 million new incidences worldwide each year and thus imposed a …
consultations with 4 million new incidences worldwide each year and thus imposed a …
The promotion of bone regeneration by nanofibrous hydroxyapatite/chitosan scaffolds by effects on integrin-BMP/Smad signaling pathway in BMSCs
In bone tissue engineering, a combination of biomimetic nanofibrous scaffolds with
renewable stem cells has recently emerged as a new strategy for promoting bone …
renewable stem cells has recently emerged as a new strategy for promoting bone …
Progress in cell-based therapies for tendon repair
The last decade has seen significant developments in cell therapies, based on permanently
differentiated, reprogrammed or engineered stem cells, for tendon injuries and degenerative …
differentiated, reprogrammed or engineered stem cells, for tendon injuries and degenerative …
Cartilage repair using hyaluronan hydrogel-encapsulated human embryonic stem cell-derived chondrogenic cells
Human embryonic stem cells (hESCs) have the potential to offer a virtually unlimited source
of chondrogenic cells for use in cartilage repair and regeneration. We have recently shown …
of chondrogenic cells for use in cartilage repair and regeneration. We have recently shown …
Efficacy of hESC-MSCs in knitted silk-collagen scaffold for tendon tissue engineering and their roles
Human embryonic stem cells (hESC) and their differentiated progenies are an attractive cell
source for transplantation therapy and tissue engineering. Nevertheless, the utility of these …
source for transplantation therapy and tissue engineering. Nevertheless, the utility of these …
MicroRNA engineered umbilical cord stem cell-derived exosomes direct tendon regeneration by mTOR signaling
Z Yao, J Li, H Xiong, H Cui, J Ning, S Wang… - Journal of …, 2021 - Springer
Background Exosomes are extracellular vesicles of nano-structures and represent an
emerging nano-scale acellular therapy in recent years. Tendon regeneration is a …
emerging nano-scale acellular therapy in recent years. Tendon regeneration is a …
Tendon‐derived stem cells (TDSCs) promote tendon repair in a rat patellar tendon window defect model
Injured tendons heal slowly and often result in the formation of mechanically and functionally
inferior fibrotic scar tissue or fibrous adhesions. This study investigated the use of tendon …
inferior fibrotic scar tissue or fibrous adhesions. This study investigated the use of tendon …