Vaccines against meningococcal diseases

M Pizza, R Bekkat-Berkani, R Rappuoli - Microorganisms, 2020 - mdpi.com
Neisseria meningitidis is the main cause of meningitis and sepsis, potentially life-threatening
conditions. Thanks to advancements in vaccine development, vaccines are now available …

Outer membrane vesicle vaccine platforms

F Micoli, R Adamo, U Nakakana - BioDrugs, 2024 - Springer
Outer membrane vesicles (OMVs) are spontaneously released by many gram-negative
bacteria during their growth and constitute an important virulence factor for bacteria, helping …

[HTML][HTML] Meningococcal vaccination: recommendations of the advisory committee on immunization practices, United States, 2020

SA Mbaeyi - MMWR. Recommendations and Reports, 2020 - cdc.gov
This report compiles and summarizes all recommendations from CDC's Advisory Committee
on Immunization Practices (ACIP) for use of meningococcal vaccines in the United States …

[HTML][HTML] Effectiveness of a meningococcal group B vaccine (4CMenB) in children

J Castilla, M García Cenoz, R Abad… - … England Journal of …, 2023 - Mass Medical Soc
Abstract Background In September 2015, the four-component, protein-based meningococcal
serogroup B vaccine (4CMenB; Bexsero) became available for private purchase in Spain …

Association of use of a meningococcus group B vaccine with group B invasive meningococcal disease among children in Portugal

FMP Rodrigues, R Marlow, MJ Simões, L Danon… - Jama, 2020 - jamanetwork.com
Importance A 4-component meningococcus group B vaccine (4CMenB) is the only vaccine
in use to prevent group B invasive meningococcal disease in young children, but no …

4CMenB journey to the 10-year anniversary and beyond

V Abitbol, F Martinón-Torres, MK Taha… - Human Vaccines & …, 2024 - Taylor & Francis
The 4-component meningococcal serogroup B (MenB) vaccine, 4CMenB, the first broadly
protective, protein-based MenB vaccine to be licensed, is now registered in more than 50 …

[HTML][HTML] Meningococcal disease in North America: updates from the global meningococcal initiative

EJ Asturias, X Bai, JA Bettinger, R Borrow, DN Castillo… - Journal of Infection, 2022 - Elsevier
This review summarizes the recent Global Meningococcal Initiative (GMI) regional meeting,
which explored meningococcal disease in North America. Invasive meningococcal disease …

Meningococcal deduced vaccine antigen reactivity (MenDeVAR) index: a rapid and accessible tool that exploits genomic data in public health and clinical …

CMC Rodrigues, KA Jolley, A Smith… - Journal of clinical …, 2020 - Am Soc Microbiol
As microbial genomics makes increasingly important contributions to clinical and public
health microbiology, the interpretation of whole-genome sequence data by nonspecialists …

Synergistic activity of antibodies in the multicomponent 4CMenB vaccine

V Viviani, A Biolchi, M Pizza - Expert Review of Vaccines, 2022 - Taylor & Francis
Introduction Vaccines based on multiple antigens often induce an immune response, which
is higher than that triggered by each single component, with antibodies acting cooperatively …

[HTML][HTML] Methods to evaluate serogroup B meningococcal vaccines: from predictions to real-world evidence

R Borrow, MK Taha, MM Giuliani, M Pizza, A Banzhoff… - Journal of Infection, 2020 - Elsevier
Serogroup B meningococci (MenB) remain a prominent cause of invasive meningococcal
disease (IMD). The protein-based multicomponent 4CMenB and the bivalent MenB-FHbp …