[HTML][HTML] Lipid and lipid raft alteration in aging and neurodegenerative diseases: a window for the development of new biomarkers

F Mesa-Herrera, L Taoro-González… - International journal of …, 2019 - mdpi.com
Lipids in the brain are major components playing structural functions as well as
physiological roles in nerve cells, such as neural communication, neurogenesis, synaptic …

Systematic review and analysis of human proteomics aging studies unveils a novel proteomic aging clock and identifies key processes that change with age

AA Johnson, MN Shokhirev, T Wyss-Coray… - Ageing research …, 2020 - Elsevier
The development of clinical interventions that significantly improve human healthspan
requires robust markers of biological age as well as thoughtful therapeutic targets. To …

[HTML][HTML] Age and cancer risk: a potentially modifiable relationship

MC White, DM Holman, JE Boehm, LA Peipins… - American journal of …, 2014 - Elsevier
This article challenges the idea that cancer cannot be prevented among older adults by
examining different aspects of the relationship between age and cancer. Although the …

Healthy aging and muscle function are positively associated with NAD+ abundance in humans

GE Janssens, L Grevendonk, RZ Perez… - Nature Aging, 2022 - nature.com
Skeletal muscle is greatly affected by aging, resulting in a loss of metabolic and physical
function. However, the underlying molecular processes and how (lack of) physical activity is …

[HTML][HTML] Multi-system physical exercise intervention for fall prevention and quality of life in pre-frail older adults: a randomized controlled trial

J Chittrakul, P Siviroj, S Sungkarat… - International journal of …, 2020 - mdpi.com
Effective interventions for indicated fall prevention are necessary for older adults with frailty.
We aimed to determine the effectiveness of a Multi-system Physical Exercise (MPE) for fall …

Human serum metabolic profiles are age dependent

Z Yu, G Zhai, P Singmann, Y He, T Xu, C Prehn… - Aging cell, 2012 - Wiley Online Library
Understanding the complexity of aging is of utmost importance. This can now be addressed
by the novel and powerful approach of metabolomics. However, to date, only a few …

The use of multiple correspondence analysis to explore associations between categories of qualitative variables in healthy ageing

PS Costa, NC Santos, P Cunha, J Cotter… - Journal of aging …, 2013 - Wiley Online Library
The main focus of this study was to illustrate the applicability of multiple correspondence
analysis (MCA) in detecting and representing underlying structures in large datasets used to …

Assessment of hydration status in a large population

S Baron, M Courbebaisse, EM Lepicard… - British Journal of …, 2015 - cambridge.org
Both acute and chronic dehydration can have important implications for human behaviour
and health. Young children, non-autonomous individuals and the elderly are at a greater risk …

Autoimmunity in the elderly: insights from basic science and clinics-a mini-review

A Watad, NL Bragazzi, M Adawi, H Amital, E Toubi… - Gerontology, 2017 - karger.com
Advancements in the field of biomedicine, including the control of infectious diseases
through antibiotics and vaccination practices and the prevention of chronic disorders, have …

Asthma in the elderly: current understanding and future research needs—a report of a National Institute on Aging (NIA) workshop

NA Hanania, MJ King, SS Braman, C Saltoun… - Journal of Allergy and …, 2011 - Elsevier
Asthma in the elderly is underdiagnosed and undertreated, and there is a paucity of
knowledge on the subject. The National Institute on Aging convened this workshop to …