Brown and brite adipocytes contribute to energy expenditure through nonshivering
thermogenesis. Though these cell types are thought to arise primarily from the de novo …

Adipose tissue is one of the largest organs, playing important roles in physiology and
pathologies of multiple diseases. However, research related to adeno-associated virus …

In obesity, the interactions between proinflammatory macrophages and adipocytes in white
adipose tissues are known to play a crucial role in disease progression by providing …

The recruitment of thermogenic brite adipocytes within white adipose tissue attenuates
obesity and metabolic comorbidities, arousing interest in understanding the underlying …

Studying brown and brite adipose tissue requires precise and reliable quantification of
cellular thermogenesis. This protocol describes the isolation of primary murine pre …

The browning of white fat has become a hot topic as it could help to lose weight and improve
metabolic health. Therefore, this study aims to explore the in vivo browning or …

Obesity and type 2 diabetes are two closely related diseases representing a serious threat
worldwide. An increase in metabolic rate through enhancement of non-shivering …

Thermogenic brown and beige adipocytes counteract obesity by enhancing energy
dissipation via uncoupling protein-1 (Ucp1). However, the effect of genetic variation on these …

Objective Obesity is characterized by excessive accumulation of white adipose tissue (WAT).
Conversely, brown adipose tissue is protective against obesity. We recently reported …

Abstract Background Differentiation of Immortalized Human Bone Marrow Mesenchymal
Stromal Cells-hTERT (iMSC3) into adipocytes is in vitro model of obesity. In our earlier …