Toward the solution of the protein structure prediction problem
Since Anfinsen demonstrated that the information encoded in a protein's amino acid
sequence determines its structure in 1973, solving the protein structure prediction problem …
sequence determines its structure in 1973, solving the protein structure prediction problem …
Principles of protein− protein interactions: what are the preferred ways for proteins to interact?
Proteins are the working horse of the cellular machinery. They are responsible for diverse
functions ranging from molecular motors to signaling. They catalyze reactions, transport …
functions ranging from molecular motors to signaling. They catalyze reactions, transport …
I-TASSER: a unified platform for automated protein structure and function prediction
The iterative threading assembly refinement (I-TASSER) server is an integrated platform for
automated protein structure and function prediction based on the sequence-to-structure-to …
automated protein structure and function prediction based on the sequence-to-structure-to …
The architecture of the spliceosomal U4/U6. U5 tri-snRNP
Abstract U4/U6. U5 tri-snRNP is a 1.5-megadalton pre-assembled spliceosomal complex
comprising U5 small nuclear RNA (snRNA), extensively base-paired U4/U6 snRNAs and …
comprising U5 small nuclear RNA (snRNA), extensively base-paired U4/U6 snRNAs and …
[HTML][HTML] The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis
F Willmund, M del Alamo, S Pechmann, T Chen… - Cell, 2013 - cell.com
In eukaryotic cells a molecular chaperone network associates with translating ribosomes,
assisting the maturation of emerging nascent polypeptides. Hsp70 is perhaps the major …
assisting the maturation of emerging nascent polypeptides. Hsp70 is perhaps the major …
A comparative assessment and analysis of 20 representative sequence alignment methods for protein structure prediction
Protein sequence alignment is essential for template-based protein structure prediction and
function annotation. We collect 20 sequence alignment algorithms, 10 published and 10 …
function annotation. We collect 20 sequence alignment algorithms, 10 published and 10 …
Protein structure prediction: when is it useful?
Y Zhang - Current opinion in structural biology, 2009 - Elsevier
Computationally predicted three-dimensional structure of protein molecules has
demonstrated the usefulness in many areas of biomedicine, ranging from approximate …
demonstrated the usefulness in many areas of biomedicine, ranging from approximate …
[图书][B] From protein structure to function with bioinformatics
DJ Rigden, DJ Rigden - 2009 - Springer
With the success of an expanding array of genome sequencing projects, the number of
known protein sequences has been increasing exponentially. However, the sequences on …
known protein sequences has been increasing exponentially. However, the sequences on …
Multiscale models quantifying yeast physiology: towards a whole-cell model
The yeast Saccharomyces cerevisiae is widely used as a cell factory and as an important
eukaryal model organism for studying cellular physiology related to human health and …
eukaryal model organism for studying cellular physiology related to human health and …
Recent progress of protein tertiary structure prediction
The prediction of three-dimensional (3D) protein structure from amino acid sequences has
stood as a significant challenge in computational and structural bioinformatics for decades …
stood as a significant challenge in computational and structural bioinformatics for decades …