We begin by summarizing several examples of antidepressants whose therapeutic actions
begin when they encounter their targets in the cytoplasm or in the lumen of an organelle …

G‐protein‐coupled receptors (GPCRs) are the most abundant receptor type in the human
body and are responsible for regulating many physiological processes, such as sensation …

Neuropeptides are ubiquitous in the nervous system. Research into neuropeptides has
been limited by a lack of experimental tools that allow for the precise dissection of their …

Abstract L-Ergothioneine (ET), the 2-thioimidazole derivative of trimethylhistidine, is
biosynthesized by select fungi and bacteria, notably Mycobacterium tuberculosis, and …

The reciprocal crosstalk between testicular Sertoli and Leydig cells plays a vital role in
supporting germ cell development and maintaining testicular characteristics and …

We report a reagentless, intensity-based S-methadone fluorescent sensor, iS-
methadoneSnFR, consisting of a circularly permuted GFP inserted within the sequence of a …

Cytisine (CTS) is a useful medicine for treating nervous disorders and smoking addiction,
and exploring a convenient method to detect CTS is of great significance for long‐term/home …

Genetically encoded fluorescent biosensors (GEFBs) proved to be reliable tracers for many
metabolites and cellular processes. In the simplest case, a fluorescent protein (FP) is …

Conventional 2D or even recently developed 3D in vitro culture models for hypothalamus
and pituitary gland cannot successfully recapitulate reciprocal neuroendocrine …

Neuropeptides are ubiquitous in the nervous system. Research into neuropeptides has
been limited by a lack of experimental tools that allow for the precise dissection of their …