Production of industrial chemicals using renewable biomass feedstock is becoming
increasingly important to address limited fossil resources, climate change and other …

Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …

Highlights•Microbial cell factories are becoming important in sustainable chemical
production.•Systems metabolic engineering allows efficient microbial cell factory …

Organic acids are important consumable materials with a wide range of applications in the
food, biopolymer and chemical industries. The global consumer organic acids market is …

Organic acids, which are chemically synthesized, are also natural intermediates in the
metabolic pathways of microorganisms, among which the tricarboxylic acid (TCA) cycle is …

The study aims to optimize cellulase (CMCase) production by Aspergillus flavus using wheat
straw, an abundantly available lignocellulosic waste, as a substrate. Three parameters, ie …

The application of rational design in reallocating metabolic flux to accumulate desired
chemicals is always restricted by the native regulatory network. In this study, recombinant …

Itaconic acid is a high potential platform chemical which is currently industrially produced by
Aspergillus terreus. Heterologous production of itaconic acid with Escherichia coli could …

The removal of excessive phosphate from water is very important to avoid eutrophication.
For this purpose, metal-organic frameworks (MOFs) have recently attracted great attention in …

A synthetic metabolic pathway suitable for the production of chorismate derivatives was
designed in Escherichia coli. An L-phenylalanine-overproducing E. coli strain was …