Noncoding RNAs as regulators of STAT3 pathway in gastrointestinal cancers: Roles in cancer progression and therapeutic response

M Ashrafizadeh, CD Mohan… - Medicinal research …, 2023 - Wiley Online Library
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and
rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic …

STAT3 as a newly emerging target in colorectal cancer therapy: Tumorigenesis, therapy response, and pharmacological/nanoplatform strategies

M Hashemi, S Abbaszadeh, M Rashidi, N Amini… - Environmental …, 2023 - Elsevier
Colorectal cancer (CRC) ranks as the third most aggressive tumor globally, and it can be
categorized into two forms: colitis-mediated CRC and sporadic CRC. The therapeutic …

Interplay of miRNAs and lncRNAs in STAT3 signaling pathway in colorectal cancer progression

O Rahbar Farzam, S Najafi, M Amini, Z Rahimi… - Cancer Cell …, 2024 - Springer
In recent decades, colorectal cancer (CRC) has turned into one of the most widespread
malignancies, and the incidence of this malignancy is expected to increase. Despite …

Long non-coding RNAs and microRNAs as crucial regulators in cardio-oncology

SB Nukala, J Jousma, Y Cho, WH Lee, SG Ong - Cell & Bioscience, 2022 - Springer
Cancer is one of the leading causes of morbidity and mortality worldwide. Significant
improvements in the modern era of anticancer therapeutic strategies have increased the …

Molecular genotyping, histopathological and immunohistochemical studies of bovine papillomatosis

HAJ Gharban, SJJ Al-Shaeli, TJ Hussen - Open Veterinary Journal, 2023 - ajol.info
Background: Bovine papillomatosis (BP) is considered the most common health problem in
large cattle farms. Aim: This study attempts to confirm clinically suspected BP in cattle by …

Exploration of the immune-related long noncoding RNA prognostic signature and inflammatory microenvironment for cervical cancer

H Yao, X Jiang, H Fu, Y Yang, Q Jin, W Zhang… - Frontiers in …, 2022 - frontiersin.org
Purpose: Our research developed immune-related long noncoding RNAs (lncRNAs) for risk
stratification in cervical cancer (CC) and explored factors of prognosis, inflammatory …

A promising new cancer marker: Long noncoding RNA EGFR-AS1

D Zhu, X Ouyang, Y Zhang, X Yu, K Su, L Li - Frontiers in oncology, 2023 - frontiersin.org
Cancer consists of a group of diseases with the salient properties of an uncontrolled cell
cycle, metastasis, and evasion of the immune response, mainly driven by the genomic …

[HTML][HTML] Combination of niclosamide and current therapies to overcome resistance for cancer: New frontiers for an old drug

J Ren, B Wang, Q Wu, G Wang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Niclosamide is a drug used to treat parasitic infections. Recent studies have shown that
niclosamide may have a wide range of clinical applications and can be used to treat cancer …

Exploring the Key Signaling Pathways and ncRNAs in Colorectal Cancer

YJ Lee, WR Kim, EG Park, DH Lee, J Kim… - International Journal of …, 2024 - mdpi.com
Colorectal cancer (CRC) is the third most prevalent cancer to be diagnosed, and it has a
substantial mortality rate. Despite numerous studies being conducted on CRC, it remains a …

Identification of a Genomic Instability‐Related Long Noncoding RNA Prognostic Model in Colorectal Cancer Based on Bioinformatic Analysis

Y Liang, HX Sun, B Ma, QK Meng - Disease markers, 2022 - Wiley Online Library
Background. In recent years, a growing body of research has revealed that long noncoding
RNAs (lncRNAs) participate in regulating genomic instability. Materials and Methods. We …