Y Sun, L Shang, QH Zhu, L Fan, L Guo - Trends in Plant Science, 2022 - cell.com
Publication of the complete genome sequence of Arabidopsis thaliana, the first plant reference genome, in December 2000 heralded the beginning of the plant genome era …
A central question in evolutionary biology is whether sponges or ctenophores (comb jellies) are the sister group to all other animals. These alternative phylogenetic hypotheses imply …
Long-read-only bacterial genome assemblies usually contain residual errors, most commonly homopolymer-length errors. Short-read polishing tools can use short reads to fix …
INTRODUCTION The characterization of the full spectrum of genetic variation is critical to understanding human health and disease. Recent technological advances have made it …
Haplotype-resolved de novo assembly is the ultimate solution to the study of sequence variations in a genome. However, existing algorithms either collapse heterozygous alleles …
While long-read sequencing allows for the complete assembly of bacterial genomes, long- read assemblies contain a variety of errors. Here, we present Trycycler, a tool which …
Long-read sequencing has the potential to transform variant detection by reaching currently difficult-to-map regions and routinely linking together adjacent variations to enable read …
High-quality and complete reference genome assemblies are fundamental for the application of genomics to biology, disease, and biodiversity conservation. However, such …
The current human reference genome, GRCh38, represents over 20 years of effort to generate a high-quality assembly, which has benefitted society,. However, it still has many …