Asymmetric aminocatalysis has been subjected to extensive development since the
renewed interest of iminium and enamine chemistry in the early 2000s. 1, 2 In this context, α …

Cobalt-mediated C–H functionalization has been the subject of extensive interest in
synthetic chemistry, but the mechanisms of many of these reactions (such as the cobalt …

Hydrogen bonding (H-bond) interactions have been regarded as a topic of vital scientific
research in areas ranging from inorganic to biological chemistry. However, the application …

We report here a Ni-catalyzed reductive coupling of aldehydes with widely available 1, 3-
dienes under visible-light photoredox dual catalysis. The homoallyic alcohols are obtained …

The Second Edition demonstrates how computational chemistry continues to shed new light
on organic chemistry The Second Edition of author Steven Bachrach's highly acclaimed …

The aldol reaction is one of the most important carbon‐carbon bond‐forming reactions in
organic chemistry. Asymmetric direct cross‐aldol reaction of two different aldehydes has …

A new catalytic asymmetric desymmetrization reaction for the synthesis of enantioenriched
derivatives of 2‐azabicyclo [3.3. 1] nonane, a key motif common to many alkaloids, has been …

The catalyst generated in situ from RuH2 (CO)(PPh3) 3,(S)-SEGPHOS, and a chiral
phosphoric acid promotes asymmetric hydrohydroxyalkylation of butadiene and affords …

Asymmetric olefin isomerization of β, γ-to α, β-unsaturated butenolides catalyzed by novel
cinchona alkaloid derivatives was investigated in-depth using density functional theory (M05 …

The trifluoromethylthio (SCF3) group enjoys a privileged role in the field of drug discovery
because its incorporation into a drug molecule often leads to significantly improved …