Multifunctional microelectronic fibers enable wireless modulation of gut and brain neural circuits

A Sahasrabudhe, LE Rupprecht, S Orguc… - Nature …, 2024 - nature.com
Progress in understanding brain–viscera interoceptive signaling is hindered by a dearth of
implantable devices suitable for probing both brain and peripheral organ neurophysiology …

Technologies for modulation of visible light and their applications

S Park, M Notaros, A Mohanty, D Kim, J Notaros… - Progress in Quantum …, 2024 - Elsevier
Control over the amplitude, phase, and spatial distribution of visible-spectrum light underlies
many technologies, but commercial solutions remain bulky, require high control power, and …

Optogenetic stimulation probes with single-neuron resolution based on organic LEDs monolithically integrated on CMOS

AJ Taal, I Uguz, S Hillebrandt, CK Moon… - Nature …, 2023 - nature.com
The use of optogenetic stimulation to evoke neuronal activity in targeted neural populations—
enabled by opsins with fast kinetics, high sensitivity and cell-type and subcellular specificity …

Recent developments in implantable neural probe technologies

H Chen, Y Fang - Mrs Bulletin, 2023 - Springer
Understanding neural circuit functions requires tools that can interrogate the activity of a
large number of neurons over extended periods of time. Implantable neural probes can …

Multifunctional Fiber‐Based Optoacoustic Emitter as a Bidirectional Brain Interface

N Zheng, Y Jiang, S Jiang, J Kim… - Advanced …, 2023 - Wiley Online Library
A bidirectional brain interface with both “write” and “read” functions can be an important tool
for fundamental studies and potential clinical treatments for neurological diseases. Herein, a …

In vivo optogenetics using a Utah Optrode Array with enhanced light output and spatial selectivity

N McAlinden, CF Reiche, AM Clark… - Journal of Neural …, 2024 - iopscience.iop.org
Objective. Optogenetics allows the manipulation of neural circuits in vivo with high spatial
and temporal precision. However, combining this precision with control over a significant …

A micro-LED array based platform for spatio-temporal optogenetic control of various cardiac models

S Junge, ME Ricci Signorini, M Al Masri, J Gülink… - Scientific Reports, 2023 - nature.com
Optogenetics relies on dynamic spatial and temporal control of light to address emerging
fundamental and therapeutic questions in cardiac research. In this work, a compact micro …

Multifunctional Tetrode-like Drug delivery, Optical stimulation, and Electrophysiology (Tetro-DOpE) probes

J Kim, E Gilbert, K Arndt, H Huang, P Oleniacz… - Biosensors and …, 2024 - Elsevier
Having reliable tools for recording and manipulating circuit activity are essential to
understand the complex patterns of neural dynamics that underlie brain function. We present …

Implantable photonic neural probes with out-of-plane focusing grating emitters

T Xue, A Stalmashonak, FD Chen, P Ding, X Luo… - Scientific Reports, 2024 - nature.com
We have designed, fabricated, and characterized implantable silicon neural probes with
nanophotonic grating emitters that focus the emitted light at a specified distance above the …

Close-packed dual-color micro-LEDs enable cortical-layer-specific bidirectional in vivo optogenetic electrophysiology

D Mao, F Sun, B Driscoll, Z Li, G Xu - Cell Reports Physical Science, 2023 - cell.com
Optogenetics promises to manipulate the brain circuitry by exciting or inhibiting the same
neurons via different colors of light (ie, bidirectionality), and furthermore, to co-work with …