Cellular senescence is a stress or damage response that causes a permanent proliferative
arrest and secretion of numerous factors with potent biological activities. This senescence …

H-Ras is a unique isoform of the Ras GTPase family, one of the most prominently mutated
oncogene families across the cancer landscape. Relative to other isoforms, though …

Rationale: Mesenchymal stromal cells (MSCs) are considered a promising resource for cell
therapy, exhibiting efficacy in ameliorating diverse bone diseases. However, most MSCs …

Apoptosis and autophagy, the mechanisms of programmed cell death, play critical roles in
physiological and pathological processes in both vertebrates and invertebrates. Apoptosis is …

Protein modification by lipid derived reactive species, or lipoxidation, is increased during
oxidative stress, a common feature observed in many pathological conditions. Biochemical …

Heightened placental inflammation and dysfunction are commonly associated in pregnant
obese women compared to their pregnant lean counterparts. The small GTPase superfamily …

Nitric oxide (NO) and electrophilic cyclopentenone prostaglandins (CyPG) are local
mediators that modulate cellular response to oxidative stress in different pathophysiological …

В последние годы понимание механизмов, участвующих в регуляции сигнальных путей
липоапоптоза, значительно расширилось. Однако многие механизмы индукции …

In recent years, the understanding of the mechanisms involved in the regulation of
lipoapoptosis signaling pathways has expanded considerably. However, many mechanisms …